Evidence map›Paper›PMID 39551707›Full record

ArticleNeuropsychopharmacology reports2025

NSW cannabis medicines advisory service retrospective enquiry analysis to inform clinical guidance resource development.

Myfanwy Graham, Edward Eden, Kelsey Maddison, Luise Lago, Samuel Allingham, Catherine J Lucas, Jennifer Schneider, Jennifer H Martin

Abstract read
In one paragraph

Article in Neuropsychopharmacology reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Myfanwy GrahamAustralian Centre for Cannabinoid Clinical and Research Excellence, Newcastle, New South Wales, Australia.ORCID https://orcid.org/0000-0003-0618-7497
Edward EdenAustralian Centre for Cannabinoid Clinical and Research Excellence, Newcastle, New South Wales, Australia.
Kelsey MaddisonCentre for Drug Repurposing and Medicines Research, School of Medicine and Public Health, The University of Newcastle, Newcastle, New South Wales, Australia.
Luise LagoAustralian Health Services Research Institute, University of Wollongong, Wollongong, New South Wales, Australia.
Samuel AllinghamAustralian Health Services Research Institute, University of Wollongong, Wollongong, New South Wales, Australia.
Catherine J LucasAustralian Centre for Cannabinoid Clinical and Research Excellence, Newcastle, New South Wales, Australia.
Jennifer SchneiderAustralian Centre for Cannabinoid Clinical and Research Excellence, Newcastle, New South Wales, Australia.
Jennifer H MartinAustralian Centre for Cannabinoid Clinical and Research Excellence, Newcastle, New South Wales, Australia.

Funding

NSW Health G2001016
6 · The paper itself

Abstract

backgroundAn innovative New South Wales government funded statewide Cannabis Medicines Advisory Service (CMAS) operated between January 2018 and June 2022. The service provided comprehensive patient-specific and evidence-based information to support health professionals in prescribing and patient care decisions. This study aimed to describe real-world data collected by CMAS.

methodsA sub-set of de-identified, patient-specific enquiries collected between January 2021 and June 2022 (n = 123/567; 21.7%) were analyzed using R version 4.2.1. Diagnosis, indication, and comorbidities were coded using Medical Dictionary for Regulatory Activities (MedDRA) terminology.

resultsMost patient-specific enquiries from medical practitioners were from general practitioners (n = 103/123; 83.7%). Female (n = 53/123; 43.1%) and male (n = 59/123; 48.0%) patients were similarly represented. Sex was not specified for 8.9% (n = 11/123) of patients. The mean age of patients was 52.1 years (range <10-90). The most common three diagnoses were osteoarthritis, anxiety, and chronic pain. Indications that were most frequently reported included chronic pain, anxiety, back pain, non-neuropathic pain, and insomnia. Comedications were most commonly non-opioid and opioid analgesics and antidepressants. Most practitioners were considering prescribing a cannabidiol (CBD) product for their patient. Cannabinoid composition selection guidance provided by CMAS was predominantly (delta-9-tetrahydrocannabinol) THC:CBD ~1:1, followed by CBD-only products. CMAS was contacted by health professionals regarding the management of potential adverse events for five patients.

conclusionThe findings of this study shed light on the information medical practitioners were seeking to inform their clinical decision-making about medical cannabis and can inform the development of clinical guidance resources.

Indexed as

Medical MarijuanaAdolescentAdultAgedAged, 80 and overCannabisChildFemaleHumansMaleMiddle AgedNew South WalesRetrospective StudiesYoung AdultMedical Marijuanaclinical guidancemedical cannabisobservational studyreal‐world evidencesafety

Identifiers

PMID39551707
PMCPMC11660764

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.