Evidence map›Paper›PMID 39551610›Full record

ArticleInfluenza and other respiratory viruses2024

Impact of Age and Comorbid Conditions on Incidence Rates of COVID-19-Associated Hospitalizations, 2020-2021.

Lisa Saiman, Edward E Walsh, Angela R Branche, Angela Barrett, Luis Alba, Sonia Gollerkeri, Julia A Schillinger, Matthew Phillips, Lyn Finelli

Abstract read
In one paragraph

Article in Influenza and other respiratory viruses, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Lisa SaimanDepartment of Pediatrics, Columbia University Irving Medical Center, New York, New York, USA.ORCID 0000-0002-7231-8451
Edward E WalshDepartment of Medicine, Division of Infectious Diseases, University of Rochester, Rochester, New York, USA.
Angela R BrancheDepartment of Medicine, Division of Infectious Diseases, University of Rochester, Rochester, New York, USA.ORCID 0000-0002-7742-5352
Angela BarrettDepartment of Pediatrics, Columbia University Irving Medical Center, New York, New York, USA.
Luis AlbaDepartment of Pediatrics, Columbia University Irving Medical Center, New York, New York, USA.
Sonia GollerkeriDepartment of Pediatrics, Columbia University Irving Medical Center, New York, New York, USA.
Julia A SchillingerMerck & Co., Inc, Rahway, New Jersey, USA.
Matthew PhillipsMerck & Co., Inc, Rahway, New Jersey, USA.
Lyn FinelliMerck & Co., Inc, Rahway, New Jersey, USA.

Funding

Merck Sharp & Dohme Corp.
6 · The paper itself

Abstract

backgroundCOVID-19-associated hospitalization rates by age and comorbid conditions can more precisely assess risk for severe illness and target prevention and treatment strategies.

methodsWe performed a retrospective study to estimate population-based COVID-19-associated hospitalization among patients by age and selected comorbid conditions in three hospital systems in Rochester and New York City (NYC), NY. Incidence rate ratios (IRR) comparing incidence rates for patients with and without these comorbidities were determined.

resultsFrom March 2020 to December 2021, 7779 patients were hospitalized with COVID-19 of whom 43.8% had ≥3 comorbid conditions. Overall annual incidence ranged from 325.3 to 965.8 per 100,000 persons. Age group-specific incidence was lowest in children 10-14 years (range 4.4-58.9) and highest in adults ≥85 years (range 2790.5-5889.6). Incidence rates for comorbid conditions generally increased with increasing age while IRR decreased with increasing age. Children in NYC 5-17 years with asthma or obesity had 3.4 and 53.3 times higher hospitalization rates, respectively, than children without these conditions. Adults in all age groups with obesity, diabetes, coronary artery disease, or congestive heart failure CHF had 1.6-4.7 times, 1.7-7.2 times, 2.0-10.1 times, or 1.7-20.2 times higher hospitalization rates, respectively, than those without these conditions. Adults ≥50 years with asthma had 1.5 to 1.8 times higher hospitalization rates than those without asthma.

conclusionsThe burden of hospitalization with COVID-19 was high, particularly among adults ≥85 years and adults with obesity, diabetes, CAD, or CHF. However, the impact of comorbidities was less in older adults. Population-based incidence rates by age and comorbidities provide more precise estimates of the benefits of vaccines and antiviral medications.

Indexed as

ComorbidityCOVID-19HospitalizationAdolescentAdultAgedAged, 80 and overAge FactorsChildChild, PreschoolFemaleHumansIncidenceInfantMaleMiddle Agedage and comorbid conditionsCOVID‐19incidence rate of hospitalization

Identifiers

PMID39551610
PMCPMC11569932

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.