Evidence map›Paper›PMID 39551249›Full record

ArticleRespiratory medicine2024

Risk factors for hospitalization in subspecialty patients with severe persistent asthma.

Nilesh Seshadri, Walter Faig, Lisa R Young, David A Hill

Abstract read
In one paragraph

Article in Respiratory medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nilesh SeshadriDivision of Pulmonary and Sleep Medicine, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Walter FaigDepartment of Biostatistics, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Lisa R YoungDivision of Pulmonary and Sleep Medicine, Children's Hospital of Philadelphia, Philadelphia, PA, USA; Department of Pediatrics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
David A HillDivision of Allergy and Immunology, Children's Hospital of Philadelphia, Philadelphia, PA, USA; Department of Pediatrics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA. Electronic address: hilld3@chop.edu.

Funding

Translational Research Support CoreP30ES013508 · NIEHS · UNIVERSITY OF PENNSYLVANIA · PI A. Clementina Mesaros · 2006 to 2026
$35.3M
Impact of Obesity on Lung Macrophage Metabolism and InflammationR01HL162715 · NHLBI · CHILDREN'S HOSP OF PHILADELPHIA · PI David Andrew Hill · 2023 to 2026
$2.4M
Midcareer Investigator Award in Patient-Oriented Research in Pediatric Rare Lung DiseasesK24HL143281 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI YOUNG, LISA R. · 2018 to 2022
$540k
NHLBI NIH HHS K24 HL143281NHLBI NIH HHS R01 HL162715NIEHS NIH HHS P30 ES013508
6 · The paper itself

Abstract

BACKGROUND AND

objectivesChildren with severe persistent asthma managed by subspecialists represent a unique patient population. The factors predisposing these children to hospital admission are poorly understood. This study aimed to identify factors associated with future emergency department (ED) visits and hospitalization in this group.

methodsA chart review was conducted for children with severe persistent asthma evaluated by a pulmonologist between January 1, 2021 and June 30, 2022. Asthma-related ED visits and hospitalizations were recorded from electronic medical records. Chi-square testing, mixed effects modeling, and logistic regression were used to analyze associations between patient characteristics and hospitalization. A secondary analysis evaluated factors contributing to ED visits.

resultsWe identified 244 unique patients with 487 pulmonary clinic visits. Of these, 56 % were black, 58 % had public insurance, and 32 % had a history of ICU admission for asthma. In the 12 months following a clinic visit, 84 (34 %) patients had an ED visit, and 46 (19 %) had at least one hospitalization. Secondhand smoke exposure (OR 2.74, 95 % CI 1.16-6.45), public insurance (OR 3.37, 95 % CI 1.46-7.82), and prior ICU admission (OR 2.29, 95 % CI 1.09-4.79) were positively associated with hospitalization for asthma exacerbation. Among hospitalized patients, bronchopulmonary dysplasia (BPD) and gastroesophageal reflux disease (GERD) were linked to shorter time to admission.

conclusionsDespite subspecialty care, children with severe persistent asthma exposed to cigarette smoke, with prior ICU admission, or with public insurance are at higher risk of subsequent ED visits and hospitalization. These findings will inform targeted interventions to prevent hospitalization in this patient population.

Indexed as

AsthmaEmergency Service, HospitalHospitalizationSeverity of Illness IndexAdolescentChildChild, PreschoolFemaleGastroesophageal RefluxHumansMaleRisk FactorsTobacco Smoke PollutionTobacco Smoke PollutionHospitalizationPediatricPulmonologistSevere persistent asthmaSubspecialist

Identifiers

PMID39551249
PMCPMC11634629

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.