Evidence map›Paper›PMID 39550801›Full record

ArticlePsychoneuroendocrinology2025

State rumination links major life stressors to acute stressor cortisol response in healthy adults.

Jacqueline Rodriguez-Stanley, Katherine Knauft, Samuele Zilioli

Abstract read
In one paragraph

Article in Psychoneuroendocrinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jacqueline Rodriguez-StanleyDepartment of Psychology, Wayne State University, Detroit, MI, USA. Electronic address: jackie.rodriguez@wayne.edu.
Katherine KnauftDepartment of Psychology, Wayne State University, Detroit, MI, USA; Department of Family Medicine and Public Health Sciences, Wayne State University, Detroit, MI, USA.
Samuele ZilioliDepartment of Psychology, Wayne State University, Detroit, MI, USA; Department of Family Medicine and Public Health Sciences, Wayne State University, Detroit, MI, USA.

Funding

UNIVERSITY OF PITTSBURGH CLINICAL AND TRANSLATIONAL SCIENCE INSTITUTE: BPCAUL1RR024153 · NCRR · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2006 to 2011
$73.9M
University of Pittsburgh Clinical and Translational Science InstituteUL1TR000005 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2012 to 2015
$50.8M
Social and psychological risk for infectious illnessR01AI066367 · NIAID · CARNEGIE-MELLON UNIVERSITY · PI COHEN, SHELDON A · 2005 to 2010
$2.8M
Social Ties and Health: Aggregating Data from Five Viral-Challenge TrialsR01AT006694 · NCCIH · CARNEGIE-MELLON UNIVERSITY · PI COHEN, SHELDON A · 2011 to 2015
$1.5M
NCATS NIH HHS UL1 TR000005NCCIH NIH HHS R01 AT006694NCRR NIH HHS UL1 RR024153NIAID NIH HHS R01 AI066367
6 · The paper itself

Abstract

Experiencing major life stressors is associated with negative health outcomes, yet the mechanisms are not fully understood. Major stressors are threatening, discrete events that can have lingering consequences on emotional and cognitive processes. This can lead to maladaptive coping strategies, such as rumination, that compromise the ability to handle subsequent stressors and disrupt the hypothalamic-pituitary-adrenal (HPA) axis response. Based on the Perseverative Cognition Hypothesis, it was hypothesized that greater exposure to major stressors would be associated with greater rumination during a laboratory stressor, which, in turn, would predict higher cortisol reactivity and peak and delayed recovery. Participants were 211 healthy adults (M

Indexed as

HydrocortisoneRumination, CognitiveStress, PsychologicalAdaptation, PsychologicalAdolescentAdultFemaleHealthy VolunteersHumansHypothalamo-Hypophyseal SystemMaleMiddle AgedPituitary-Adrenal SystemSalivaYoung AdultHydrocortisoneAcute stressorCortisolHPA axisMajor life eventsPerseverative cognitionRumination

Identifiers

PMID39550801
PMCPMC11830531

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.