Evidence map›Paper›PMID 39550489›Full record

ReviewBritish journal of cancer2025

UK guidelines for the management of bone sarcomas.

Craig Gerrand, Fernanda Amary, Hanny A Anwar, Bernadette Brennan, Palma Dileo, Maninder Singh Kalkat, Martin G McCabe, Anna Louise McCullough, Michael C Parry, Anish Patel and 4 more

Abstract readReview
In one paragraph

Review in British journal of cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Review
  3. Article
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  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Observational
  12. Article
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  14. Article
  15. Article
  16. Review
  17. Review
  18. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Craig GerrandBone and Soft Tissue Tumour Service, Royal National Orthopaedic Hospital, Stanmore, Middlesex, HA7 4LP, UK. Craig.gerrand@nhs.net.ORCID http://orcid.org/0000-0003-3043-4507
Fernanda AmaryBone and Soft Tissue Tumour Service, Royal National Orthopaedic Hospital, Stanmore, Middlesex, HA7 4LP, UK.ORCID http://orcid.org/0000-0002-6707-8246
Hanny A AnwarBone and Soft Tissue Tumour Service, Royal National Orthopaedic Hospital, Stanmore, Middlesex, HA7 4LP, UK.
Bernadette BrennanThe Christie NHS Foundation Trust, Manchester, M20 4BX, UK.
Palma DileoDepartment of Oncology, University College London Hospital NHS Foundation Trust, London, NW1 2BU, UK.
Maninder Singh KalkatDepartment of Thoracic Surgery, Queen Elizabeth Hospital, Birmingham, B15 2GW, UK.
Martin G McCabeThe Christie NHS Foundation Trust, Manchester, M20 4BX, UK.ORCID http://orcid.org/0000-0002-5138-0707
Anna Louise McCulloughDepartment of Orthopaedics, Woodend Hospital, Eday Road, Aberdeen, AB15 6XS, UK.
Michael C ParryRoyal Orthopaedic Hospital, Bristol Road South, Birmingham, B31 2AP, UK.
Anish PatelRoyal Orthopaedic Hospital, Bristol Road South, Birmingham, B31 2AP, UK.
Beatrice M SeddonDepartment of Oncology, University College London Hospital NHS Foundation Trust, London, NW1 2BU, UK.ORCID http://orcid.org/0000-0001-5364-9143
Jennifer M SherriffCancer Centre, Queen Elizabeth Hospital, Birmingham, UK.
Roberto TiraboscoBone and Soft Tissue Tumour Service, Royal National Orthopaedic Hospital, Stanmore, Middlesex, HA7 4LP, UK.
Sandra J StraussDepartment of Oncology, University College London Hospital NHS Foundation Trust, London, NW1 2BU, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This document is an update of the British Sarcoma Group guidelines (2016) and provides a reference standard for the clinical care of UK patients with primary malignant bone tumours (PMBT) and giant cell tumours (GCTB) of bone. The guidelines recommend treatments that are effective and should be available in the UK, and support decisions about management and service delivery. The document represents a consensus amongst British Sarcoma Group members in 2024. Key recommendations are that bone pain, or a palpable mass should always lead to further investigation and that patients with clinical or radiological findings suggestive of a primary bone tumour at any anatomic site should be referred to a specialist centre and managed by an accredited bone sarcoma multidisciplinary team. Treatment recommendations are provided for the major tumour types and for localised, metastatic and recurrent disease. Follow-up schedules are suggested.

Indexed as

Bone NeoplasmsOsteosarcomaSarcomaHumansPractice Guidelines as TopicUnited Kingdom

Identifiers

PMID39550489
PMCPMC11723950

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.