Evidence map›Paper›PMID 39550208›Full record

SynthesisSchizophrenia bulletin2026

Psychotic Experiences and Risk of Suicidal Thoughts and Behaviors: A Systematic Review and Meta-Analysis of Longitudinal Population Studies.

Kirstie O'Hare, Kubra Fadiloglu, Ulla Lång, Colm Healy, Mary Cannon, Jordan DeVylder, Ian Kelleher

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Schizophrenia bulletin, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kirstie O'HareCentre for Clinical Brain Sciences, University of Edinburgh, EH16 4SB Edinburgh, United Kingdom.ORCID 0000-0002-1166-9792
Kubra FadilogluCentre for Clinical Brain Sciences, University of Edinburgh, EH16 4SB Edinburgh, United Kingdom.
Ulla LångCentre for Clinical Brain Sciences, University of Edinburgh, EH16 4SB Edinburgh, United Kingdom.
Colm HealyCentre for Clinical Brain Sciences, University of Edinburgh, EH16 4SB Edinburgh, United Kingdom.
Mary CannonDepartment of Psychiatry, Royal College of Surgeons in Ireland, University of Medicine and Health Sciences, Dublin 9, Dublin, Ireland.
Jordan DeVylderSilver School of Social Work, New York University, 10003 New York, NY, United States.
Ian KelleherCentre for Clinical Brain Sciences, University of Edinburgh, EH16 4SB Edinburgh, United Kingdom.

Funding

Academy of Medical Sciences APR8\1005The Health Research Board ECSA-2020-005UK Department for Business, Energy and Industrial Strategy
6 · The paper itself

Abstract

background and hypothesisSince a prior systematic review and meta-analysis reported an association between psychotic experiences (PEs) and suicidal thoughts and behaviors, a large number of new studies have been published on the topic, including several novel studies on the association between PEs and transition from suicidal ideation to attempt. STUDY

designTwo authors independently searched PubMed, Embase, CINAHL, and PsycINFO databases from inception until July 2023, conducted data extraction, and assessed study quality using the Newcastle-Ottawa Quality Assessment Scale. Random-effects models were used to calculate pooled odds ratios (ORs) for the association of PEs and subsequent suicide ideation, suicide attempts, suicide death, and transition from suicidal ideation to attempt, first for the total population, and second stratified by age group. Secondary analyses assessed the mediating role of co-occurring psychopathology. STUDY

resultsTwenty studies from 18 different samples (n = 81,861) were identified. Individuals who reported PEs had increased odds of subsequent suicidal ideation (k = 12, OR = 1.90, 95% CI = 1.65-2.19), suicide attempt (k = 13, OR = 2.95, 95% CI = 2.21-3.94), transition from suicidal ideation to suicide attempt (k = 3, OR = 2.83, 95% CI = 1.60-4.99), and suicide death (k = 1, OR = 4.39, 95% CI = 1.63-11.80). This heightened risk was stable across childhood, adolescence, and adulthood. PEs predicted suicide attempts over and above co-occurring psychopathology (k = 8, OR = 2.85, 95% CI = 2.06-3.95).

conclusionsIndividuals reporting PEs are at increased risk of all types of suicidal thoughts and behaviors. In addition, PEs are particularly important risk markers for future suicidal behaviors, including in individuals already reporting suicidal ideation. This risk is in excess of what is explained by co-occurring psychopathology.

Indexed as

Psychotic DisordersSuicidal IdeationSuicide, AttemptedSuicide, CompletedAdultHumansLongitudinal Studiesideation to attemptpsychosissuicidal ideationsuicidesuicide attempt

Identifiers

PMID39550208
PMCPMC12809804

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.