Evidence map›Paper›PMID 39549872›Full record

ArticleIndian pacing and electrophysiology journal

Lesion characteristics of long application time ablation using unipolar half-normal saline irrigation and bipolar normal saline irrigation.

Takumi Kasai, Osamu Saitoh, Ayaka Oikawa, Naomasa Suzuki, Yasuhiro Ikami, Yuki Hasegawa, Sou Otsuki, Takayuki Inomata, Hiroshi Furushima, Masaomi Chinushi

Abstract read
In one paragraph

Article in Indian pacing and electrophysiology journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Takumi KasaiCardiovascular Research of Graduate School of Health Sciences, Niigata University School of Medicine, Niigata, Japan.
Osamu SaitohCardiovascular Research of Graduate School of Health Sciences, Niigata University School of Medicine, Niigata, Japan.
Ayaka OikawaCardiovascular Research of Graduate School of Health Sciences, Niigata University School of Medicine, Niigata, Japan.
Naomasa SuzukiDepartment of Cardiovascular Biology and Medicine, Niigata University School of Medicine, Niigata, Japan.
Yasuhiro IkamiDepartment of Cardiovascular Biology and Medicine, Niigata University School of Medicine, Niigata, Japan.
Yuki HasegawaDepartment of Cardiovascular Biology and Medicine, Niigata University School of Medicine, Niigata, Japan.
Sou OtsukiDepartment of Cardiovascular Biology and Medicine, Niigata University School of Medicine, Niigata, Japan.
Takayuki InomataDepartment of Cardiovascular Biology and Medicine, Niigata University School of Medicine, Niigata, Japan.
Hiroshi FurushimaCardiovascular Research of Graduate School of Health Sciences, Niigata University School of Medicine, Niigata, Japan.
Masaomi ChinushiCardiovascular Research of Graduate School of Health Sciences, Niigata University School of Medicine, Niigata, Japan. Electronic address: masaomi@clg.niigata-u.ac.jp.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionUnipolar radiofrequency (RF) ablation using half-normal saline irrigation (UNIP-HNS) and bipolar RF ablation using normal saline irrigation (BIP-NS) are effective to treat arrhythmias from inside thick myocardium. However, differences between these two ablations when using a long application time had not fully been studied.

methodsUNIP-HNS, BIP-NS and unipolar RF ablation using normal saline irrigation (UNIP-NS) were applied for 120 s (30 W and 20-g contact) to porcine endocardial wall (≧15.0 mm thickness).

resultsAll ablations (30 applications each in UNIP-HNS and BIP-NS, and 20 applications in UNIP-NS) were successfully accomplished without steam-pop. Total impedance decline was largest in BIP-NS followed by UNIP-HNS and UNIP-NS. UNIP-HNS created larger surface lesions and greater maximum lesion width under the surface than those by UNIP-NS and BIP-NS. Endocardial lesion depth in UNIP-HNS and BIP-NS were deeper than that in UNIP-NS, but with no difference between UNIP-HNS and BIP-NS, when selecting non-transmural lesions. Similar results were obtained when all lesions (non-transmural and transmural) were included and endocardial lesion depth of the transmural lesions (13/30 applications of BIP-NS) was estimated as 50 % of the myocardial thickness. Lesion length in the transverse myocardial wall (endocardial plus epicardial lesions) was greatest in BIP-NS.

conclusionsLonger application time ablation (30 W) targeting the thick myocardium was performable in UNIP-HNS and BIP-NS. Since a transmural lesion and/or a deeper lesion into the myocardial wall are created, BIP-NS is preferable if two ablation catheters can be positioned on either side of the target.

Indexed as

Bipolar ablationHalf-normal saline irrigationRadiofrequency ablation

Identifiers

PMID39549872
PMCPMC11962260

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.