Evidence map›Paper›PMID 39549180›Full record

ReviewInternational urology and nephrology2025

Discussion on the treatment of diabetic kidney disease based on the "gut-fat-kidney" axis.

Yaping He, Dengke Jia, Wenying Chen, Juan Liu, Congrong Liu, Xiaowei Shi

Abstract readReview
PubMed Publisher
In one paragraph

Review in International urology and nephrology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yaping HeGansu University of Chinese Medicine, Lanzhou, 730000, China.
Dengke JiaLanzhou University Second Clinical Medical College, Lanzhou University, Lanzhou, 730000, China.
Wenying ChenGansu University of Chinese Medicine, Lanzhou, 730000, China.
Juan LiuGansu University of Chinese Medicine, Lanzhou, 730000, China.
Congrong LiuGansu University of Chinese Medicine, Lanzhou, 730000, China.
Xiaowei ShiDepartment of Endocrinology, Gansu Provincial Hospital of Traditional Chinese Medicine, Lanzhou, 730000, China. lzhsxw@163.com.ORCID http://orcid.org/0009-0001-0067-3278

Funding

Gansu Association for Science and Technology Youth Science and Technology Talent Promotion Project GXH202026-11Lanzhou City Talent Innovation and Entrepreneurship Project (2019-RC-62)National Natural Science Foundation of China (No.81960888, No.82360884, No.82360955)
6 · The paper itself

Abstract

Diabetic kidney disease is the main cause of end-stage renal disease, and its prevention and treatment are still a major clinical problem. The human intestine has a complex flora of hundreds of millions of microorganisms, and intestinal microorganisms, and their derivatives are closely related to renal inflammatory response, immune response, and material metabolism. Brown adipose tissue is the main part of adaptive thermogenesis. Recent studies have shown that activating brown fat by regulating intestinal flora has good curative effects in diabetic kidney disease-related diseases. As an emerging medical concept, the "gut-fat-kidney" axis has received increasing attention in diabetic kidney disease and related diseases. However, the specific mechanism involved needs further study. A new theoretical basis for the prevention and treatment of diabetic kidney disease is presented in this article, based on the "gut-fat-kidney" axis.

Indexed as

Adipose Tissue, BrownDiabetic NephropathiesGastrointestinal MicrobiomeKidneyHumansBrown adipose tissueDiabetic kidney diseaseGut–fat–kidney axisIntestinal floraMechanismReview

Identifiers

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.