Evidence map›Paper›PMID 39548985›Full record

ArticleACS applied bio materials2024

Design and Biofunctionalization of Cloud Sponge-Inspired Scaffolds for Enhanced Bone Cell Performance.

Philipp Zimmermann, Peter Schulze, Annette G Beck-Sickinger, Yuliya Khrunyk

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS applied bio materials, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Philipp ZimmermannEngineering Faculty, Leipzig University of Applied Sciences (HTWK), Karl Liebknecht Str. 134, D-04277 Leipzig, Germany.
Peter SchulzeEngineering Faculty, Leipzig University of Applied Sciences (HTWK), Karl Liebknecht Str. 134, D-04277 Leipzig, Germany.
Annette G Beck-SickingerInstitute of Biochemistry, Faculty of Life Sciences, Leipzig University, Brüderstrs. 34, D-04103 Leipzig, Germany.ORCID 0000-0003-4560-8020
Yuliya KhrunykInstitute of Biochemistry, Faculty of Life Sciences, Leipzig University, Brüderstrs. 34, D-04103 Leipzig, Germany.ORCID 0000-0001-9059-1198

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With the increasing age of our population, which is linked to a higher incidence of musculoskeletal diseases, there is a massive clinical need for bone implants. Porous scaffolds, usually offering a lower stiffness and allowing for the ingrowth of blood vessels and nerves, serve as an attractive alternative to conventional implants. Natural porous skeletons from marine sponges represent an array of evolutionarily optimized patterns, inspiring the design of biomaterials. In this study, cloud sponge-inspired scaffolds were designed and printed from a photocurable polymer, Clear Resin. These scaffolds were biofunctionalized by mussel-derived peptide MP-RGD, a recently developed peptide that contains a cyclic, bioactive RGD cell adhesion motif and catechol moieties, which provide the anchoring of the peptide to the surface. In

Indexed as

Biocompatible MaterialsMaterials TestingTissue ScaffoldsAnimalsCell ProliferationCells, CulturedHumansOligopeptidesOsteoblastsParticle SizePoriferaPorosityarginyl-glycyl-aspartic acidBiocompatible MaterialsOligopeptidesbone cellsClear Resincyclic RGDmussel peptide MPporositysponge-inspired scaffolds

Identifiers

PMID39548985
PMCPMC11653246

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.