Evidence map›Paper›PMID 39548761›Full record

ReviewJournal of burn care & research : official publication of the American Burn Association2025

Evidence Supporting Conservative Scar Management Interventions Following Burn Injury: A Review Article.

Zoë Edger-Lacoursière, Mengyue Zhu, Stéphanie Jean, Elisabeth Marois-Pagé, Bernadette Nedelec

Registry-linked trialAbstract readReview
In one paragraph

Review in Journal of burn care & research : official publication of the American Burn Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07578883 (Effects of the Scar Tissue Mobilization on Scar Thickness, Pliability and Quality of Life in Children With Upper Extremity Burns.), which is not on this map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07578883 narecruitingnot on this mapstarted 2026, after this paper: background citation

Effects of the Scar Tissue Mobilization on Scar Thickness, Pliability and Quality of Life in Children With Upper Extremity Burns.

TypeinterventionalSponsorRiphah International UniversityRan2026 to 2026Enrolled15ConditionsBurn ScarArmsScar tissue mobilization
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. [Practice guideline for adult burn rehabilitation nursing (2026 edition)].Zhonghua shao shang yu chuang mian xiu fu za zhi · 2026
    Guideline
  2. Trial
  3. Rehabilitation Evaluation and Treatment for Skin Graft Complications of the Genitalia.Journal of burn care & research : official publication of the American Burn Association · 2026
    Article
  4. Review
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zoë Edger-LacoursièreSchool of Physical and Occupational Therapy, McGill University, Montréal, Québec, Canada.ORCID 0000-0001-5945-6078
Mengyue ZhuDepartment of Orthopedics, Zhongnan Hospital of Wuhan University, Wuhan, China.ORCID 0009-0003-4475-1869
Stéphanie JeanHôpital de réadaptation Villa Medica, Montréal, QC, Canada.ORCID 0000-0001-8908-1713
Elisabeth Marois-PagéHôpital de réadaptation Villa Medica, Montréal, QC, Canada.
Bernadette NedelecSchool of Physical and Occupational Therapy, McGill University, Montréal, Québec, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Conservative management for hypertrophic scars (HSc) and scar contractures is of utmost importance to optimally reintegrate burn survivors into society. Many conservative treatment interventions have been described in the literature for the management of HSc. Recent advancements in the literature pertaining to postburn scarring and HSc formation have advanced our understanding of the mechanisms that support or refute the use of common rehabilitation treatment modalities after burn injury. This is particularly relevant for recent advancements in the fields of mechanotransduction and neurogenic inflammation, resulting in the need for rehabilitation clinicians to reflect upon commonly employed treatment interventions. The aim of this review article is to summarize and clinically apply the evidence that supports or refutes the use of common conservative treatment interventions for scar management employed after burn injury. The following treatments are discussed, and mechanotransduction and neurogenic inflammation concepts are highlighted: (1) edema management (compression, positioning/elevation, pumping exercises, retrograde massage, and manual edema mobilization); (2) pressure therapy (including custom fabricated pressure garments, inserts, face masks, and other low-load long-duration orthotic devices); (3) gels or gel sheets; (4) combined pressure therapy and gels; (5) serial casting; (6) scar massage; and (7) passive stretching. This review supports the following statements: (1) Compression for edema reduction should be initiated 48-72 hours postinjury and continued for wounds that require longer than 21 days to heal until scar maturation; (2) Elevation, pumping exercises, and retrograde massage/MEM should be used in combination with other edema management techniques; (3) Custom-fabricated pressure garments should be applied once the edema is stabilized and adequate healing has occurred. Garments should be monitored on a regular basis to ensure that optional pressure, >15 mm Hg, is maintained, adding inserts when necessary. The wearing time should be >16 hours/day; (4) Gels for postburn scar management should extend beyond the scar; (5) Serial casting should be applied when contractures interfere with function; (6) Forceful scar massage should be avoided early in the wound healing process or when the scar is inflamed or breaks down; and (7) Other treatment modalities should be prioritized over passive stretching for scar management.

Indexed as

BurnsCicatrix, HypertrophicConservative TreatmentCicatrixContractureHumansburn scar managementhypertrophic scarmechanotransductionneurogenic inflammationrehabilitation

Identifiers

PMID39548761
PMCPMC12344095

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.