Evidence map›Paper›PMID 39548490›Full record

ArticleBMC veterinary research2024

Stability of closed and needle-punctured vials of Porvac® subunit vaccine against classical swine fever subjected to thermal stress.

Talía Sardina-González, Milagros Vargas-Hernández, Yusmel Sordo-Puga, Paula Naranjo-Valdéz, María Pilar Rodríguez-Moltó, Mary Karla Méndez-Orta, Mara Laura Hernández-García, Elaine Santana-Rodríguez, William Pena-Guimaraes, Alain Moreira-Rubio and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC veterinary research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Talía Sardina-González *Departamento de Biotecnología Animal, Centro de Ingeniería Genética y Biotecnología, P.O. Box 6162, Ave 31 e/ 158 y 190, Cubanacán, Playa, La Habana, 1600, Cuba.
Milagros Vargas-Hernández *Departamento de Biotecnología Animal, Centro de Ingeniería Genética y Biotecnología, P.O. Box 6162, Ave 31 e/ 158 y 190, Cubanacán, Playa, La Habana, 1600, Cuba. milagros.vargas@cigb.edu.cu.
Yusmel Sordo-PugaDepartamento de Biotecnología Animal, Centro de Ingeniería Genética y Biotecnología, P.O. Box 6162, Ave 31 e/ 158 y 190, Cubanacán, Playa, La Habana, 1600, Cuba.
Paula Naranjo-ValdézUnidad Central de Laboratorios de Salud Animal, La Habana, 11400, Cuba.
María Pilar Rodríguez-MoltóDepartamento de Biotecnología Animal, Centro de Ingeniería Genética y Biotecnología, P.O. Box 6162, Ave 31 e/ 158 y 190, Cubanacán, Playa, La Habana, 1600, Cuba.
Mary Karla Méndez-OrtaDepartamento de Biotecnología Animal, Centro de Ingeniería Genética y Biotecnología, P.O. Box 6162, Ave 31 e/ 158 y 190, Cubanacán, Playa, La Habana, 1600, Cuba.
Mara Laura Hernández-GarcíaDepartamento de Biotecnología Animal, Centro de Ingeniería Genética y Biotecnología, P.O. Box 6162, Ave 31 e/ 158 y 190, Cubanacán, Playa, La Habana, 1600, Cuba.
Elaine Santana-RodríguezDepartamento de Biotecnología Animal, Centro de Ingeniería Genética y Biotecnología, P.O. Box 6162, Ave 31 e/ 158 y 190, Cubanacán, Playa, La Habana, 1600, Cuba.
William Pena-GuimaraesCentro de Ingeniería Genética y Biotecnología de Camagüey, Camagüey, Cuba.
Alain Moreira-RubioCentro de Ingeniería Genética y Biotecnología de Camagüey, Camagüey, Cuba.
Rosaili Mateu-HernándezDepartamento de Química Física, Centro de Ingeniería Genética y Biotecnología, Ave 31 e/ 158 y 190, Cubanacán, Playa, La Habana, 1600, Cuba.
Ania Cabrales-RicoDepartamento de Química Física, Centro de Ingeniería Genética y Biotecnología, Ave 31 e/ 158 y 190, Cubanacán, Playa, La Habana, 1600, Cuba.
Carlos A DuarteDepartamento de Biotecnología Animal, Centro de Ingeniería Genética y Biotecnología, P.O. Box 6162, Ave 31 e/ 158 y 190, Cubanacán, Playa, La Habana, 1600, Cuba.
Danny Pérez-PérezDepartamento de Biotecnología Animal, Centro de Ingeniería Genética y Biotecnología, P.O. Box 6162, Ave 31 e/ 158 y 190, Cubanacán, Playa, La Habana, 1600, Cuba.
Marisela Suárez-PedrosoDepartamento de Biotecnología Animal, Centro de Ingeniería Genética y Biotecnología, P.O. Box 6162, Ave 31 e/ 158 y 190, Cubanacán, Playa, La Habana, 1600, Cuba.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundClassical Swine Fever (CSF) is still one of the most economically important viral diseases of pigs. In endemic countries, the disease is controlled mostly through vaccination; hence, the availability of safe and effective vaccines is of utmost importance. Vaccines intended for application in developing countries must also be thermally stable, since the infrastructure needed to maintain a cold chain in those countries is usually lacking. Porvac

resultsThe vaccine subjected to all these conditions did not show significant changes in the physicochemical properties of the emulsion; did not produce local or systemic adverse reactions in pigs, and the chromatographic profile of the recovered antigen was preserved. All vaccinated swine developed neutralizing antibody titers ≥ 1:1000 at 28 days post vaccination.

conclusionsPorvac

Indexed as

Classical Swine FeverDrug StabilityVaccines, SubunitViral VaccinesAnimalsAntibodies, ViralClassical Swine Fever VirusHot TemperatureSwineAntibodies, ViralVaccines, SubunitViral VaccinesClassical swine feverMontanideNPLAThermal stressVaccination efficacyVaccine stabilityVirus

Identifiers

PMID39548490
PMCPMC11566387

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.