ArticleNature microbiology2024
Metabolites from intact phage-infected Synechococcus chemotactically attract heterotrophic marine bacteria.
Article in Nature microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
7 citing papers in PubMed.
- Article
- Marine bacteria degrade viral particles as a source of nitrogen, phosphorus, and sulfur-rich dissolved organic matter.ISME communications · 2026Article
- Phage resistance mutations in a marine bacterium impact biogeochemically relevant cellular processes.Nature microbiology · 2026Article
- Virocell resource manipulation under nutrient limitation.mSystems · 2025Article
- Article
- Slower swimming promotes chemotactic encounters between bacteria and small phytoplankton.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Bacterial chemotaxis toward virus-infected cyanobacteria.Nature microbiology · 2024Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
Chemical cues mediate interactions between marine phytoplankton and bacteria, underpinning ecosystem-scale processes including nutrient cycling and carbon fixation. Phage infection alters host metabolism, stimulating the release of chemical cues from intact plankton, but how these dynamics impact ecology and biogeochemistry is poorly understood. Here we determine the impact of phage infection on dissolved metabolite pools from marine cyanobacteria and the subsequent chemotactic response of heterotrophic bacteria using time-resolved metabolomics and microfluidics. Metabolites released from intact, phage-infected Synechococcus elicited strong chemoattraction from Vibrio alginolyticus and Pseudoalteromonas haloplanktis, especially during early infection stages. Sustained bacterial chemotaxis occurred towards live-infected Synechococcus, contrasted by no discernible chemotaxis towards uninfected cyanobacteria. High-throughput microfluidics identified 5'-deoxyadenosine and 5'-methylthioadenosine as key attractants. Our findings establish that, before lysis, phage-infected picophytoplankton release compounds that attract motile heterotrophic bacteria, suggesting a mechanism for resource transfer that might impact carbon and nutrient fluxes across trophic levels.
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Registered trials
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