Evidence map›Paper›PMID 39548234›Full record

ArticleScientific reports2024

Machine learning-based model for predicting the occurrence and mortality of nonpulmonary sepsis-associated ARDS.

Jinfeng Lin, Chunfeng Gu, Zhaorui Sun, Suyan Zhang, Shinan Nie

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In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 4 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jinfeng LinDepartment of Emergency Medicine, Jinling Clinical Medical College of Nanjing Medical University, Nanjing, 210016, Jiangsu, China.
Chunfeng GuCtrip Infrastructure Service, Trip.com Group Ltd, Shanghai, 200335, China.
Zhaorui SunDepartment of Emergency Medicine, Jinling Clinical Medical College of Nanjing Medical University, Nanjing, 210016, Jiangsu, China.
Suyan ZhangCritical Care Medicine, Nantong Third People's Hospital, Affiliated Nantong Hospital 3 of Nantong University, Nantong, 226000, Jiangsu, China. ntsyzsy@163.com.
Shinan NieDepartment of Emergency Medicine, Jinling Clinical Medical College of Nanjing Medical University, Nanjing, 210016, Jiangsu, China. shn_nie@sina.com.

Funding

Natural Science Foundation of Jiangsu Province BK20211136
6 · The paper itself

Abstract

objectiveThe objective was to establish a machine learning-based model for predicting the occurrence and mortality of nonpulmonary sepsis-associated ARDS.

methods80% of sepsis patients selected randomly from the MIMIC-IV database, without prior pulmonary conditions and with nonpulmonary infection sites, were used to construct prediction models through machine learning techniques (including K-nearest neighbour, extreme gradient boosting, support vector machine, deep neural network, and decision tree methods). The remaining 20% of patients were utilized to validate the model's accuracy. Additionally, local data were employed for further model validation.

resultsA total of 11,409 patients were included, with the most common type of infection being bloodstream infection. A total of 7,632 (66.9%) patients developed nonpulmonary sepsis-associated ARDS (NPS-ARDS). Patients with NPS-ARDS had significantly longer ICU stays (6.2 ± 5.2 days vs. 4.4 ± 3.7 days, p < 0.01) and higher 28-day mortality rates (19.5% vs. 14.9%, p < 0.01). Both internal and external validation demonstrated that the model constructed with the extreme gradient boosting method had high accuracy. In the internal validation, the model predicted NPS-ARDS and mortality in such patients with accuracies of 77.5% and 71.8%, respectively. In the external validation, the model predicted NPS-ARDS and mortality in these patients with accuracies of 78.0% and 81.4%, respectively.

conclusionThe model established via the extreme gradient boosting method can predict the occurrence and mortality of nonpulmonary sepsis-associated ARDS to a certain extent.

Indexed as

Machine LearningRespiratory Distress SyndromeSepsisAgedFemaleHumansIntensive Care UnitsMaleMiddle AgedNeural Networks, ComputerPrognosisAcute respiratory distress syndromeExternal validationInternal validationMachine learningMortalityPredictive modelSepsis

Identifiers

PMID39548234
PMCPMC11568264

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.