Evidence map›Paper›PMID 39548134›Full record

ArticleScientific reports2024

Liver knockout of MCU leads to greater dysregulation of lipid metabolism in MAFLD.

Qichao Liao, Yurou Zhang, Tingli Pan, Yu Sun, Siqi Liu, Zhiwang Zhang, Yixing Li, Lin Yu, Zupeng Luo, Yang Xiao and 11 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Mitochondrial Calcium Signaling in Hepatocyte Health and Disease.Cold Spring Harbor perspectives in biology · 2026
    Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Qichao Liao *College of Animal Science and Technology, Guangxi University, Nanning, China.
Yurou Zhang *College of Animal Science and Technology, Guangxi University, Nanning, China.
Tingli PanInstitute of Digestive Disease, Guangxi Academy of Medical Sciences, The People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, China.
Yu SunInstitute of Digestive Disease, Guangxi Academy of Medical Sciences, The People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, China.
Siqi LiuInstitute of Digestive Disease, Guangxi Academy of Medical Sciences, The People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, China.
Zhiwang ZhangInstitute of Digestive Disease, Guangxi Academy of Medical Sciences, The People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, China.
Yixing LiCollege of Animal Science and Technology, Guangxi University, Nanning, China.
Lin YuInstitute of Digestive Disease, Guangxi Academy of Medical Sciences, The People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, China.
Zupeng LuoInstitute of Digestive Disease, Guangxi Academy of Medical Sciences, The People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, China.
Yang XiaoInstitute of Digestive Disease, Guangxi Academy of Medical Sciences, The People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, China.
Xinyi QiInstitute of Digestive Disease, Guangxi Academy of Medical Sciences, The People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, China.
Tianyu JiangInstitute of Digestive Disease, Guangxi Academy of Medical Sciences, The People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, China.
Songtao SuInstitute of Digestive Disease, Guangxi Academy of Medical Sciences, The People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, China.
Shi LiuInstitute of Digestive Disease, Guangxi Academy of Medical Sciences, The People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, China.
Xinyu QiInstitute of Digestive Disease, Guangxi Academy of Medical Sciences, The People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, China.
Xiangling LiInstitute of Digestive Disease, Guangxi Academy of Medical Sciences, The People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, China.
Turtushikh DambaSchool of Pharmacy, Mongolian National University of Medical Sciences, Ulan Bator, 14200, Mongolia.
Khongorzul BatchuluunCenter for Research and Development of Institute of Biomedical Sciences, Mongolian National University of Medical Sciences, Ulan Bator, 14200, Mongolia.
Yunxiao LiangInstitute of Digestive Disease, Guangxi Academy of Medical Sciences, The People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, China.
Suosu WeiDepartment of Scientific Cooperation of Guangxi Academy of Medical Sciences, The People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, 530021, Guangxi Zhuang Autonomous Region, People's Republic of China. sswei@gxams.org.cn.
Lei ZhouInstitute of Digestive Disease, Guangxi Academy of Medical Sciences, The People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, China. zhoulei@gxu.edu.cn.

Funding

Guangxi Academy of Medical Sciences high-level Talents Foundation YKY-GCRC-202302Guangxi Science Foundation for Distinguished Young Scholars 2020GXNSFFA297008National Key R&D Program of China 2023YFE0100800
6 · The paper itself

Abstract

Metabolic-associated fatty liver disease (MAFLD) is a common chronic condition that poses a significant threat to human health. Mitochondrial dysfunction, particularly involving the mitochondrial Ca

Indexed as

Calcium ChannelsLipid MetabolismLiverMice, KnockoutNon-alcoholic Fatty Liver DiseaseAnimalsDiet, High-FatDisease Models, AnimalMaleMiceMice, Inbred C57BLOxidative StressTriglyceridesCalcium Channelsmitochondrial calcium uniporterTriglyceridesFat liverLipid dysregulationLipid transport-associatedMAFLDMCU

Identifiers

PMID39548134
PMCPMC11568211

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.