Evidence map›Paper›PMID 39548128›Full record

ArticleScientific reports2024

Comparative metabolic profiling and quantitative analysis of metabolites in different tissues of Ajuga turkestanica by ESI-UHPLC-QqTOF-MS and NMR.

Nilufar Z Mamadalieva, Michal Šoral, Elana Kysil, Pauline Stark, Andrej Frolov, Ludger A Wessjohann

Abstract readComparative Study
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nilufar Z MamadalievaNew Uzbekistan University, Movarounnahr Str 1, Mirzo-Ulug'bek District, 100000, Tashkent, Uzbekistan. nmamadalieva@yahoo.com.
Michal ŠoralAnalytical Department, Institute of Chemistry, Slovak Academy of Sciences, Dúbravská cesta 9, SK-845 38, Bratislava, Slovak Republic.
Elana KysilDepartment of Bioorganic Chemistry, Leibniz Institute of Plant Biochemistry, Weinberg 3, 06120, Halle, Germany.
Pauline StarkDepartment of Bioorganic Chemistry, Leibniz Institute of Plant Biochemistry, Weinberg 3, 06120, Halle, Germany.
Andrej FrolovDepartment of Bioorganic Chemistry, Leibniz Institute of Plant Biochemistry, Weinberg 3, 06120, Halle, Germany.
Ludger A WessjohannDepartment of Bioorganic Chemistry, Leibniz Institute of Plant Biochemistry, Weinberg 3, 06120, Halle, Germany. wessjohann@ipb-halle.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ajuga turkestanica preparations are used as anti-aging cosmeceuticals and for medicinal purposes. Herein we describe the characterization and quantification of its metabolites in different organs using UHPLC-MS and NMR spectroscopy. A total of 51 compounds belonging to various phytochemical classes (11 flavonoids, 10 ecdysteroids, 9 diterpenes, 6 fatty acids, 5 iridoids, 3 phenylpropanoids, 3 sugars, 2 phenolics, 1 coumarin, 1 triterpene) were annotated and tentatively identified by UHPLC-ESI-QqTOF-MS/MS of methanolic extracts obtained separately from the organs. 1D and 2D NMR spectroscopy independently confirmed the identity of six major compounds. The abundances of these main constituents in flowers, fruits, leaves, roots, seeds, and stems were compared and quantified using

Indexed as

AjugaMagnetic Resonance SpectroscopyMetabolomicsPlant ExtractsSpectrometry, Mass, Electrospray IonizationChromatography, High Pressure LiquidFlavonoidsHumansIridoidsMetabolomePhytochemicalsPlant LeavesTandem Mass SpectrometryFlavonoidsIridoidsPhytochemicalsPlant ExtractsAjuga turkestanicaBiological activityMetabolite annotationMetabolite profilingNMRUHPLC-MS

Identifiers

PMID39548128
PMCPMC11568135

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.