Evidence map›Paper›PMID 39548113›Full record

ReviewNPJ Regenerative medicine2024

Heart regeneration from the whole-organism perspective to single-cell resolution.

Xiaoxin Chen, Xiaochen Zhong, Guo N Huang

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in NPJ Regenerative medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Xiaoxin ChenCardiovascular Research Institute and Department of Physiology, University of California, San Francisco, San Francisco, CA, USA.ORCID http://orcid.org/0000-0003-3092-7010
Xiaochen ZhongCardiovascular Research Institute and Department of Physiology, University of California, San Francisco, San Francisco, CA, USA.ORCID http://orcid.org/0009-0008-6015-9538
Guo N HuangCardiovascular Research Institute and Department of Physiology, University of California, San Francisco, San Francisco, CA, USA. Guo.Huang@ucsf.edu.ORCID http://orcid.org/0000-0002-4335-9123

Funding

Molecular control of cardiac regenerative potentialR01HL138456 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Guo Huang · 2018 to 2026
$5.1M
PB Diversity Supplement Joseph MorenoR01HL160819 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Guo Huang · 2022 to 2026
$3.0M
American Heart Association (American Heart Association, Inc.) 828442NHLBI NIH HHS R01 HL138456NHLBI NIH HHS R01 HL160819U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute (NHLBI) R01HL157280
6 · The paper itself

Abstract

Cardiac regenerative potential in the animal kingdom displays striking divergence across ontogeny and phylogeny. Here we discuss several fundamental questions in heart regeneration and provide both a holistic view of heart regeneration in the organism as a whole, as well as a single-cell perspective on intercellular communication among diverse cardiac cell populations. We hope to provide valuable insights that advance our understanding of organ regeneration and future therapeutic strategies.

Identifiers

PMID39548113
PMCPMC11568173

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.