Evidence map›Paper›PMID 39548070›Full record

ArticleNature communications2024

VSV

Jahanara Rajwani, Daniil Vishnevskiy, Madison Turk, Victor Naumenko, Chris Gafuik, Dae-Sun Kim, Laura K Mah, Shannon Snelling, Gerone A Gonzales, Jingna Xue and 14 more

Abstract read
In one paragraph

Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Jahanara RajwaniArnie Charbonneau Cancer Institute; University of Calgary, Calgary, AB, T2N 4N1, Canada.ORCID 0000-0003-3409-4319
Daniil VishnevskiyArnie Charbonneau Cancer Institute; University of Calgary, Calgary, AB, T2N 4N1, Canada.ORCID 0000-0002-5778-215X
Madison TurkArnie Charbonneau Cancer Institute; University of Calgary, Calgary, AB, T2N 4N1, Canada.ORCID 0000-0001-9195-8406
Victor NaumenkoArnie Charbonneau Cancer Institute; University of Calgary, Calgary, AB, T2N 4N1, Canada.
Chris GafuikArnie Charbonneau Cancer Institute; University of Calgary, Calgary, AB, T2N 4N1, Canada.
Dae-Sun KimArnie Charbonneau Cancer Institute; University of Calgary, Calgary, AB, T2N 4N1, Canada.
Laura K MahArnie Charbonneau Cancer Institute; University of Calgary, Calgary, AB, T2N 4N1, Canada.
Shannon SnellingArnie Charbonneau Cancer Institute; University of Calgary, Calgary, AB, T2N 4N1, Canada.
Gerone A GonzalesDepartment of Biochemistry and Molecular Biology, Cumming School of Medicine; University of Calgary, Calgary, AB, T2N 4N1, Canada.
Jingna XueThe Calvin, Joan and Phoebe Snyder Institute for Chronic Disease; University of Calgary, Calgary, AB, T2N 4N1, Canada.
Ayan ChandaArnie Charbonneau Cancer Institute; University of Calgary, Calgary, AB, T2N 4N1, Canada.ORCID 0000-0002-2692-8558
Kyle G PottsArnie Charbonneau Cancer Institute; University of Calgary, Calgary, AB, T2N 4N1, Canada.
Hayley M TodescoArnie Charbonneau Cancer Institute; University of Calgary, Calgary, AB, T2N 4N1, Canada.ORCID 0000-0002-6905-3667
Keith C K LauDepartment of Microbiology, Immunology, and Infectious Diseases, Cumming School of Medicine; University of Calgary, Calgary, AB, T2N 4N1, Canada.
Karys M HildebrandArnie Charbonneau Cancer Institute; University of Calgary, Calgary, AB, T2N 4N1, Canada.ORCID 0000-0002-1075-7950
Jennifer A ChanArnie Charbonneau Cancer Institute; University of Calgary, Calgary, AB, T2N 4N1, Canada.ORCID 0000-0001-9798-1551
Shan LiaoThe Calvin, Joan and Phoebe Snyder Institute for Chronic Disease; University of Calgary, Calgary, AB, T2N 4N1, Canada.
Michael J MonumentArnie Charbonneau Cancer Institute; University of Calgary, Calgary, AB, T2N 4N1, Canada.
Martin HyrczaArnie Charbonneau Cancer Institute; University of Calgary, Calgary, AB, T2N 4N1, Canada.
Pinaki BoseArnie Charbonneau Cancer Institute; University of Calgary, Calgary, AB, T2N 4N1, Canada.ORCID 0000-0002-8338-2838
Craig N JenneThe Calvin, Joan and Phoebe Snyder Institute for Chronic Disease; University of Calgary, Calgary, AB, T2N 4N1, Canada.ORCID 0000-0001-8637-0181
Johnathan CantonThe Calvin, Joan and Phoebe Snyder Institute for Chronic Disease; University of Calgary, Calgary, AB, T2N 4N1, Canada.
Franz J ZempArnie Charbonneau Cancer Institute; University of Calgary, Calgary, AB, T2N 4N1, Canada.
Douglas J MahoneyArnie Charbonneau Cancer Institute; University of Calgary, Calgary, AB, T2N 4N1, Canada. djmahone@ucalgary.ca.ORCID 0000-0002-0642-992X

Funding

cGMP Manufacture, Fill-Finish, Release, Analytical and Stability Testing and Stability Program of a Nanoparticle Based HIV Envelope Vaccine75N93022D00005 · NIAID · INTERNATIONAL AIDS VACCINE INITIATIVE · PI HASSELL, THOMAS · 2022 to 2025
$8.0M
Task Area A shall encompass annual follow-up of cohort members, clinical events investigations, study operations, and data analysis and manuscript writing. If implemented, Task A.1 will provide fundin75N92020D00005 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI WATSON, KAROL E · 2020 to 2025
$5.1M
Alberta Children's Hospital Foundation ACHF21-0845Canadian Cancer Society Research Institute (Société Canadienne du Cancer) ACTION-20Gouvernement du Canada | Canadian Institutes of Health Research (Instituts de Recherche en Santé du Canada) 156035Gouvernement du Canada | Canadian Institutes of Health Research (Instituts de Recherche en Santé du Canada) 420828NHLBI NIH HHS 75N92020D00005NIAID NIH HHS 75N93022D00005NIAID NIH HHS 75N93023D00005NIDA NIH HHS 75N95020D00005ORFDO NIH HHS 75N99020D00005
6 · The paper itself

Abstract

Oncolytic viruses (OV) are designed to selectively infect and kill cancer cells, while simultaneously eliciting antitumour immunity. The mechanism is expected to originate from infected cancer cells. However, recent reports of tumour regression unaccompanied by cancer cell infection suggest a more complex mechanism of action. Here, we engineered vesicular stomatitis virus (VSV)

Indexed as

CD8-Positive T-LymphocytesDendritic CellsOncolytic VirotherapyOncolytic VirusesAnimalsCell Line, TumorCross-PrimingCytokinesFemaleHumansLymphocyte ActivationMiceMice, Inbred C57BLNeoplasmsProgrammed Cell Death 1 ReceptorVesicular stomatitis Indiana virusCytokinesProgrammed Cell Death 1 Receptor

Identifiers

PMID39548070
PMCPMC11567966

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.