Evidence map›Paper›PMID 39548041›Full record

ReviewTopics in current chemistry (Cham)2024

A Comprehensive Exploration of the Synergistic Relationship between DMSO and Peroxide in Organic Synthesis.

Sumit Kumar, Ashutosh Dey, Barnali Maiti, Soumyadip Das, Sai Deepak Pasuparthy, Kishor Padala

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In one paragraph

Review in Topics in current chemistry (Cham), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sumit KumarDepartment of Chemistry, School of Advanced Sciences, VIT, Vellore, 632014, Tamil Nadu, India.
Ashutosh DeyDepartment of Chemistry, School of Advanced Sciences, VIT, Vellore, 632014, Tamil Nadu, India.
Barnali MaitiDepartment of Chemistry, School of Advanced Sciences, VIT, Vellore, 632014, Tamil Nadu, India. barnalimaiti.m@gmail.com.
Soumyadip DasDepartment of Chemistry, School of Advanced Sciences, VIT, Vellore, 632014, Tamil Nadu, India.
Sai Deepak PasuparthyDepartment of Chemistry, School of Advanced Sciences, VIT, Vellore, 632014, Tamil Nadu, India.
Kishor PadalaDepartment of Chemistry, Central Tribal University of Andhra Pradesh, Kondakarakam Village, Cantonment, Vizianagaram, Andhra Pradesh, 535003, India. kishor.padala@ctuap.ac.in.

Funding

CELL SURFACE ADHESION AND CELL INTERACTIONSK04HD000454 · NICHD · UNIVERSITY OF TEXAS SW MED CTR/DALLAS · PI SNELL, WILLIAM J · 1985 to 1986
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Human Resource Development Centre, Council of Scientific And Industrial Research 02(0454)/21/EMR-IIScience and Engineering Research Board CRG/20211/003497VIT University SG20220031
6 · The paper itself

Abstract

In the realm of organic synthesis, reagents can serve not only as solvents but also as synthons. Dimethyl sulfoxide (DMSO) is recognized for its efficiency in this dual capacity, enabling diverse chemical transformations. DMSO can generate various synthons, including methyl, methylene, methine, oxygen, and methyl sulfoxide, broadening the accessible compound repertoire. Activation of DMSO as a reagent relies heavily on synergies with secondary agents like peroxide, persulfate, or iodine. Recent years have witnessed a surge in innovative synthetic techniques harnessing the synergistic interplay of DMSO and peroxide, leading to environmentally friendly and cost-effective reactions with mild conditions. This review highlights the synergistic effects of DMSO and peroxides (up to 2023), detailing their activation mechanisms and the generation of various synthons, along with numerous reported derivatives. Although this topic has received considerable attention in recent years, there are numerous discrepancies and a plethora of possibilities yet to be explored. We anticipate that this review will significantly support researchers in advancing their innovations to a greater extent in the future.

Indexed as

Dimethyl SulfoxidePeroxidesMolecular StructureDimethyl SulfoxidePeroxidesActivationDMSOHeterocyclesPeroxideSynthon

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.