Evidence map›Paper›PMID 39548039›Full record

ArticleDigestive diseases and sciences2025

The Impact of Obesity on the Prevalence and Complications of Perianal Fistulas of Crohn's Disease.

Jennifer Youn, Katie Hsia, Surya Khadilkar, Tanya Zeina, Puja Rai, Akash Rastogi, Sureya Hussani, Samara Spence, Pranay Adavelly, Jason Yanes and 4 more

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Article in Digestive diseases and sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Jennifer YounDepartment of Medicine, Tufts Medical Center, 800 Washington St, Boston, MA, 02111, USA. jennifer.youn@tuftsmedicine.org.
Katie HsiaDepartment of Medicine, Tufts Medical Center, 800 Washington St, Boston, MA, 02111, USA.
Surya KhadilkarDepartment of Medicine, Tufts Medical Center, 800 Washington St, Boston, MA, 02111, USA.
Tanya ZeinaDivision of Gastroenterology, Tufts University School of Medicine, Boston, USA.
Puja RaiDivision of Gastroenterology, Tufts University School of Medicine, Boston, USA.
Akash RastogiDepartment of Medicine, Tufts Medical Center, 800 Washington St, Boston, MA, 02111, USA.
Sureya HussaniTufts University School of Medicine, Boston, USA.
Samara SpenceTufts University School of Medicine, Boston, USA.
Pranay AdavellyTufts University School of Medicine, Boston, USA.
Jason YanesTufts University School of Medicine, Boston, USA.
Jacob KotlierTufts University School of Medicine, Boston, USA.
Benjamin SweigartTufts Medical Center, Tufts Clinical and Translational Science Institute, Boston, USA.
Alexander N LevySection of Digestive Diseases, Yale University, New Haven, USA.
Sonia FriedmanDivision of Gastroenterology, Tufts University School of Medicine, Boston, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe incidence of obesity in patients with inflammatory bowel disease (IBD) is increasing and there are limited data on the impact of obesity on perianal fistulas in Crohn's disease (CD).

aimsWe aim to examine the relationship between obesity and the prevalence and complications of Crohn's perianal fistulas.

methodsWe conducted a cross-sectional study of CD patients treated at a tertiary care center from 2012 to 2022. Obesity was defined as maximum BMI > 30 kg/m

resultsIn all, 704 patients with CD were included; 31.1% were obese. There was no significant association between obesity and prevalence of perianal fistulas (p = 0.719), complex fistulas (p = 0.144), history of perianal surgery (p = 0.146), ≥ 1 perianal surgeries (p = 0.220), fecal diversion (p = 0.705), or median time to first perianal surgery (p = 0.192). Increasing BMI category was not associated with the prevalence of perianal fistulas (p = 0.944), complex fistulas (p = 0.089), perianal surgery (p = 0.583), ≥ 1 perianal surgeries (p = 0.114), fecal diversion (p = 0.542), or median time to first perianal surgery (p = 0.486). When comparing those with perianal fistulas to those without, there was no significant difference in rates of obesity (p = 0.876).

conclusionThere was no association between obesity and the prevalence and complications of Crohn's perianal fistulas.

Indexed as

Crohn DiseaseObesityRectal FistulaAdultBody Mass IndexCross-Sectional StudiesFemaleHumansMaleMiddle AgedPrevalenceYoung AdultCrohn’s diseaseObesityPerianal fistula

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.