Evidence map›Paper›PMID 39547960›Full record

ArticleLasers in medical science2024

Effect of photobiomodulation and corticopuncture methods on tooth displacement and gene expression: animal study.

Bruna Maria Chiappetta Vanderlei, Martha Carolina Torres, Ney Paredes, Aguinaldo Silva Garcez, Pollyanna Tombini Montaldi Pavini, Selly Sayuri Suzuki, Won Moon

Abstract read
PubMed Publisher
In one paragraph

Article in Lasers in medical science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Bruna Maria Chiappetta VanderleiDepartment of the Post-graduation in Orthodontics, Faculdade São Leopoldo Mandic, Campinas, SP, Brazil. bruna.chiappetta@gmail.com.ORCID http://orcid.org/0009-0002-8259-3227
Martha Carolina TorresSchool of Dentistry, University of California, Los Angeles, CA, USA.
Ney ParedesSchool of Dentistry, University of California, Los Angeles, CA, USA.
Aguinaldo Silva GarcezDepartment of Microbiology, Faculdade São Leopoldo Mandic, Campinas, SP, Brazil.
Pollyanna Tombini Montaldi PaviniLaboratory of Pathology, Faculdade São Leopoldo Mandic, Campinas, SP, Brazil.
Selly Sayuri SuzukiDepartment of Orthodontics and Post-graduation in Orthodontics, Faculdade São Leopoldo Mandic, Campinas, SP, 52020-060, Brazil.
Won MoonDepartment of Orthodontics, at Institute of Oral Health Science, Ajou University School of Medicine, Suwon, Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThe aim of this study was to evaluate the expression levels of vascular endothelial growth factor (VEGF), Peroxiredoxin 1 (PRX1), glucose transporter 1 (GLUT1) and type I collagen (COL1) and the rate of tooth movement comparing 3 accelerated tooth movement (ATM) methods: Corticopuncture (CP), photobiomodulation (PBM) and the combined technique (CP + PBM) on days 1, 3, 7 and 14.

methodsOrthodontic tooth movement was induced in 24 male Wistar rats. CP procedure included three perforations: two in the palate and one mesial to the molars. GaAlAs diode laser irradiation was performed on days 0, 2, 4 and 6, totaling 4 irradiations. 14 days (810 nm, 100 mW, 15 s). Gingival tissue was collected from the cervical area of both first molars and qPCR was performed to isolate and quantify mRNA levels.

resultsAll ATM groups showed increased tooth displacement compared to control after 14 days (20% for PBM; 40% for CP and 60% for CP + PBM). PBM showed higher VEGF expression on days 1,3 and 7 followed by CP and CP + PBM. PRX1 levels increased on days 1 and 3 in PBM and CP + PBM. GLUT1 increased on day 3 in all groups. No difference was found on levels of VEGF, PRX1 and GLUT1 among the groups on day 14, except for COL1 which increased significantly in PBM group.

conclusionAll ATM methods showed higher expression of all of VEGF, PRX1, GLUT1, COL1 than control group. PBM and CP + PBM groups had more expression related to angiogenesis, glucose uptake, oxidative stress and collagen synthesis.

Indexed as

Collagen Type IGlucose Transporter Type 1Low-Level Light TherapyRats, WistarTooth Movement TechniquesVascular Endothelial Growth Factor AAnimalsGene ExpressionGingivaLasers, SemiconductorMalePuncturesRatsCollagen Type IGlucose Transporter Type 1Slc2a1 protein, ratVascular Endothelial Growth Factor AAccelerated tooth movementAngiogenesisLasertherapyLow-level laserMicro-osteoperforationOxidative stress

Identifiers

PMID39547960

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.