Evidence map›Paper›PMID 39547953›Full record

ArticleZoonoses and public health2025

Antimicrobial Resistance and Zoonotic Potential of Nontyphoidal Salmonella From Household Dogs.

Sophia M Kenney, Nkuchia M M'ikanatha, Erika Ganda

Abstract read
In one paragraph

Article in Zoonoses and public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Cross-species genomic analysis ofOne health (Amsterdam, Netherlands) · 2026
    Article
  2. Article
  3. Article
  4. Frontiers in veterinary science · 2026
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sophia M KenneyDepartment of Animal Science, The Pennsylvania State University, University Park, Pennsylvania, USA.ORCID 0000-0002-9361-7477
Nkuchia M M'ikanathaDepartment of Food Science, The Pennsylvania State University, University Park, Pennsylvania, USA.
Erika GandaDepartment of Animal Science, The Pennsylvania State University, University Park, Pennsylvania, USA.

Funding

Computation, Bioinformatics, and Statistics (CBIOS) Training ProgramT32GM102057 · NIGMS · PENNSYLVANIA STATE UNIVERSITY, THE · PI CHIAROMONTE, FRANCESCA, GIRIRAJAN, SANTHOSH · 2013 to 2022
$2.7M
FDA HHS U01 FD006253FDA HHS U01 FD007142NIGMS NIH HHS T32 GM102057NIH HHSU.S. Department of AgricultureU.S. Food and Drug Administration
6 · The paper itself

Abstract

backgroundCompanion animals, like household dogs, are an overlooked transmission point for zoonotic pathogens such as nontyphoidal Salmonella (NTS). Given the proximity of dogs to humans and the use of critically important antibiotics in companion animal medicine, household dogs represent a risk for the spread of antimicrobial-resistant (AMR) Salmonella. METHODS AND

resultsTo this end, we aimed to leverage existing biosurveillance infrastructure to investigate AMR and the zoonotic potential of NTS isolated from dogs and humans. We identified all NTS strains isolated from domestic dogs via the Veterinary Laboratory Investigation and Response Network between May 2017 and March 2023 (N = 87), and spatiotemporally matched strains isolated from humans in the NCBI Pathogen Isolate Browser (N = 77). These 164 strains, collected from 17 states in the United States, formed the basis of our analysis. Strains isolated from dogs comprised diverse serovars, with most being clinically relevant to human health. All strains possessed AMR determinants for drug classes deemed critically or highly important by the World Health Organization. We identified sixteen NTS isolates from humans closely related to ≥1 of six dog-associated strains.

conclusionsCollectively, our data emphasize the importance of antimicrobial stewardship and sustained biosurveillance beyond human- and agriculture-associated veterinary medicine, using a One-Health framework that accounts for all transmission points including companion animals.

Indexed as

Anti-Bacterial AgentsDog DiseasesDrug Resistance, BacterialSalmonellaSalmonella Infections, AnimalAnimalsDogsHumansSalmonella InfectionsUnited StatesZoonosesAnti-Bacterial Agentsantibiotic resistancegenomicsSalmonella

Identifiers

PMID39547953
PMCPMC11698641

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.