Evidence map›Paper›PMID 39547937›Full record

ArticleJournal of cardiovascular electrophysiology2025

The Impact of Coronary Ischemia Assessment on Outcomes in Those With Scar-Dependent Ventricular Tachycardia.

Michael C Waight, Davide Fabbricatore, Elijah R Behr, Manav Sohal, Anthony C Li, Magdi M Saba

Abstract read
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Article in Journal of cardiovascular electrophysiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Michael C WaightCity St George's University of London, London, UK.ORCID 0000-0001-8714-5808
Davide FabbricatoreSt George's University Hospitals NHS Foundation Trust, London, UK.ORCID 0000-0002-5622-3233
Elijah R BehrCity St George's University of London, London, UK.ORCID 0000-0002-8731-2853
Manav SohalSt George's University Hospitals NHS Foundation Trust, London, UK.ORCID 0000-0002-5771-5504
Anthony C LiCity St George's University of London, London, UK.ORCID 0000-0001-5516-1117
Magdi M SabaCity St George's University of London, London, UK.ORCID 0000-0002-0134-4214

Funding

St George's Hospital Charity RES 20 21 001.
6 · The paper itself

Abstract

backgroundGuidance and outcomes of coronary ischemia assessment (IA) in those with structural heart disease (SHD), presenting with monomorphic ventricular tachycardia (MMVT) is unclear.

objectivesTo assess the impact of IA on arrhythmic and non-arrhythmic outcomes in those with SHD.

methodsPatients presenting with MMVT over a 6-year period to a tertiary center were retrospectively analyzed. Propensity score-matched analysis was performed comparing those undergoing IA to those who did not. The primary endpoint was a composite of VT recurrence, appropriate ICD therapy, heart failure hospitalization, and death. Secondary analysis of the individual components of the composite was performed. Kaplan-Meier, univariate and multivariate analysis was performed to compare the two groups and derive predictors of poor outcomes.

resultsTwo hundred and seventeen patients (57.6% ICM) were analyzed. 55.8% underwent IA. Following propensity score-matching, 120 patients remained. At 12 months, freedom from the primary endpoint was 68.3% of those undergoing IA versus 43.3% who did not, p < 0.001, multivariate HR 0.56 (0.34-0.92). This was driven by a reduction in all-cause mortality, with a 12-month survival of 98.3% in those undergoing IA versus 86.5% in those not undergoing IA (p < 0.01). Coronary intervention was associated with a significantly higher event-free 12-month survival compared to those who did not undergo intervention (82.4% vs 51.5%, respectively, p = 0.01).

conclusionsPatients with SHD presenting MMVT who undergo an IA have significantly improved freedom from VT recurrence, appropriate ICD therapies, HF hospitalization, and death compared to those who do not, driven by a reduction in mortality.

Indexed as

CicatrixTachycardia, VentricularAgedDefibrillators, ImplantableElectric CountershockFemaleHeart RateHumansMaleMiddle AgedPredictive Value of TestsProgression-Free SurvivalRecurrenceRetrospective StudiesRisk AssessmentRisk Factorscoronary angiogramischemia assessmentventricular tachycardia

Identifiers

PMID39547937
PMCPMC11726999

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.