Evidence map›Paper›PMID 39547823›Full record

Trial reportThe American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry2025

Testing the Efficacy of a Culturally Adapted Family Dementia Caregiver Intervention (REACH VN): Results From a Cluster Randomized Controlled Trial in Northern Vietnam.

Huong Nguyen, Hung Trong Nguyen, Ngoc Bich Nguyen, Duyen Tran, Danielle J Harvey, Binh Thanh Nguyen, Binh Thi Thanh Nguyen, Anh Ngoc Nguyen, Chinh Thi Hong Nguyen, Thu Thi Hoai Nguyen and 11 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Huong NguyenSchool of Nursing (HN), University of Minnesota, Minneapolis, MN. Electronic address: nguy4786@umn.edu.
Hung Trong NguyenVietnam National Geriatric Hospital (HTN, NBN, BTN, BTTN, ANN, CTHN, TTN, TLN, ATPN, NHN, ALN, YHL, PQN, TAN, TP), Hanoi, Vietnam; Department of Neurology (HTN), Department of Geriatrics (TTHN, TAN, TP), Hanoi Medical University, Hanoi, Vietnam.
Ngoc Bich NguyenVietnam National Geriatric Hospital (HTN, NBN, BTN, BTTN, ANN, CTHN, TTN, TLN, ATPN, NHN, ALN, YHL, PQN, TAN, TP), Hanoi, Vietnam.
Duyen TranDepartment of Psychiatry and Behavioral Sciences (DT, LH), University of California, Davis, Sacramento, CA.
Danielle J HarveyDepartment of Public Health Sciences (DJH), University of California, Davis, Davis, CA.
Binh Thanh NguyenVietnam National Geriatric Hospital (HTN, NBN, BTN, BTTN, ANN, CTHN, TTN, TLN, ATPN, NHN, ALN, YHL, PQN, TAN, TP), Hanoi, Vietnam.
Binh Thi Thanh NguyenVietnam National Geriatric Hospital (HTN, NBN, BTN, BTTN, ANN, CTHN, TTN, TLN, ATPN, NHN, ALN, YHL, PQN, TAN, TP), Hanoi, Vietnam.
Anh Ngoc NguyenVietnam National Geriatric Hospital (HTN, NBN, BTN, BTTN, ANN, CTHN, TTN, TLN, ATPN, NHN, ALN, YHL, PQN, TAN, TP), Hanoi, Vietnam.
Chinh Thi Hong NguyenVietnam National Geriatric Hospital (HTN, NBN, BTN, BTTN, ANN, CTHN, TTN, TLN, ATPN, NHN, ALN, YHL, PQN, TAN, TP), Hanoi, Vietnam.
Thu Thi Hoai NguyenVietnam National Geriatric Hospital (HTN, NBN, BTN, BTTN, ANN, CTHN, TTN, TLN, ATPN, NHN, ALN, YHL, PQN, TAN, TP), Hanoi, Vietnam; Department of Neurology (HTN), Department of Geriatrics (TTHN, TAN, TP), Hanoi Medical University, Hanoi, Vietnam.
Thuy Le NguyenVietnam National Geriatric Hospital (HTN, NBN, BTN, BTTN, ANN, CTHN, TTN, TLN, ATPN, NHN, ALN, YHL, PQN, TAN, TP), Hanoi, Vietnam.
Anh Thi Phuong NguyenVietnam National Geriatric Hospital (HTN, NBN, BTN, BTTN, ANN, CTHN, TTN, TLN, ATPN, NHN, ALN, YHL, PQN, TAN, TP), Hanoi, Vietnam.
Ngoc Hung NguyenVietnam National Geriatric Hospital (HTN, NBN, BTN, BTTN, ANN, CTHN, TTN, TLN, ATPN, NHN, ALN, YHL, PQN, TAN, TP), Hanoi, Vietnam.
Anh Lan NguyenVietnam National Geriatric Hospital (HTN, NBN, BTN, BTTN, ANN, CTHN, TTN, TLN, ATPN, NHN, ALN, YHL, PQN, TAN, TP), Hanoi, Vietnam.
Yen Hai LuongVietnam National Geriatric Hospital (HTN, NBN, BTN, BTTN, ANN, CTHN, TTN, TLN, ATPN, NHN, ALN, YHL, PQN, TAN, TP), Hanoi, Vietnam.
Bien Huu NguyenHai Duong General Hospital (BHN), Hai Duong, Vietnam.
Phong Quy NguyenVietnam National Geriatric Hospital (HTN, NBN, BTN, BTTN, ANN, CTHN, TTN, TLN, ATPN, NHN, ALN, YHL, PQN, TAN, TP), Hanoi, Vietnam.
Laura N GitlinCollege of Nursing and Health Professions, Drexel University (LNG), Philadelphia, PA.
Trung Anh NguyenVietnam National Geriatric Hospital (HTN, NBN, BTN, BTTN, ANN, CTHN, TTN, TLN, ATPN, NHN, ALN, YHL, PQN, TAN, TP), Hanoi, Vietnam; Department of Neurology (HTN), Department of Geriatrics (TTHN, TAN, TP), Hanoi Medical University, Hanoi, Vietnam.
Thang PhamVietnam National Geriatric Hospital (HTN, NBN, BTN, BTTN, ANN, CTHN, TTN, TLN, ATPN, NHN, ALN, YHL, PQN, TAN, TP), Hanoi, Vietnam; Department of Neurology (HTN), Department of Geriatrics (TTHN, TAN, TP), Hanoi Medical University, Hanoi, Vietnam.
Ladson HintonDepartment of Psychiatry and Behavioral Sciences (DT, LH), University of California, Davis, Sacramento, CA.

Funding

UC Davis Clinical and Translational Science CenterUL1TR001860 · NCATS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI KENYON, NICHOLAS J., LYLES, COURTNEY REES · 2016 to 2025
$47.3M
Advancing Alzheimer’s family caregiving interventions and research capacity in VietnamR01AG064688 · NIA · UNIVERSITY OF CALIFORNIA AT DAVIS · PI HINTON, WALTER LADSON, NGUYEN, HUONG · 2019 to 2023
$3.4M
NCATS NIH HHS UL1 TR001860NIA NIH HHS R01 AG064688
6 · The paper itself

Abstract

objectivesVietnam faces an unprecedented increase in people living with dementia but lacks evidence-based family dementia caregiver interventions. We tested the efficacy of a culturally adapted family caregiver intervention (REACH VN) in Northern Vietnam.

methodsIn this randomized controlled trial, clusters (communes) were assigned to

resultsOverall, 350 caregivers from 40 clusters (21 intervention, 19 enhanced control) enrolled and 330 (94.3%) completed 3-month assessments. At 3 months, the REACH VN intervention group had lower PHQ-4 (p <0.001) but not ZBI-12 (p = 0.05) scores compared to control. At 6 months, the intervention group had lower ZBI-12 (p = 0.002) but not PHQ-4 (p = 0.5) scores. PSS-10 and PHQ-15 scores were also improved at 3 months (p = 0.007, p <0.001 respectively) for the REACH VN intervention group compared with control but not at 6 months.

conclusionsREACH VN improved outcomes in family caregivers in Vietnam at 3 months although improvement was not sustained for most outcomes at 6 months.

Indexed as

CaregiversDementiaPsychological DistressStress, PsychologicalAdultAgedCulturally Competent CareFemaleHumansMaleMiddle AgedVietnamAlzheimer's diseaseDementiaFamily caregivingGlobal healthLow- and middle-income countriesNonpharmacological interventionsVietnam

Identifiers

PMID39547823
PMCPMC11903202

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.