Evidence map›Paper›PMID 39547228›Full record

ArticleCell2024

STK19 positions TFIIH for cell-free transcription-coupled DNA repair.

Tycho E T Mevissen, Maximilian Kümmecke, Ernst W Schmid, Lucas Farnung, Johannes C Walter

Abstract read
In one paragraph

Article in Cell, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed.

  1. DNA Repair Mechanisms.Methods in molecular biology (Clifton, N.J.) · 2027
    Review
  2. Review
  3. Topology Resetting During Transcription-Coupled Nucleotide Excision Repair.International journal of molecular sciences · 2026
    Review
  4. Structure of cytoplasmic RNA polymerase II.Nature communications · 2026
    Article
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  11. Review
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  16. Reconstitution of genome remodeling usingFrontiers in cell and developmental biology · 2026
    Review
  17. Review
  18. Xenopus laevis Egg Extracts.Methods in molecular biology (Clifton, N.J.) · 2026
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Tycho E T MevissenDepartment of Biological Chemistry and Molecular Pharmacology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA; Howard Hughes Medical Institute, Boston, MA, USA.
Maximilian KümmeckeDepartment of Cell Biology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA.
Ernst W SchmidDepartment of Biological Chemistry and Molecular Pharmacology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA.
Lucas FarnungDepartment of Cell Biology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA. Electronic address: lucas_farnung@hms.harvard.edu.
Johannes C WalterDepartment of Biological Chemistry and Molecular Pharmacology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA; Howard Hughes Medical Institute, Boston, MA, USA. Electronic address: johannes_walter@hms.harvard.edu.

Funding

The Fanconi anemia pathway: role in DNA interstrand cross-link repairR01HL098316 · NHLBI · HARVARD MEDICAL SCHOOL · PI Johannes Walter · 2010 to 2026
$6.3M
Visualizing mechanisms at the intersection of chromatin, transcription, and epigeneticsDP2ES036404 · NIEHS · HARVARD MEDICAL SCHOOL · PI Lucas Farnung · 2023 to 2026
$2.5M
Howard Hughes Medical InstituteNHLBI NIH HHS R01 HL098316NIEHS NIH HHS DP2 ES036404
6 · The paper itself

Abstract

In transcription-coupled nucleotide excision repair (TC-NER), stalled RNA polymerase II (RNA Pol II) binds CSB and CRL4

Indexed as

Cryoelectron MicroscopyDNA RepairRNA Polymerase IITranscription Factor TFIIHTranscription, GeneticAnimalsCell-Free SystemDNA DamageHumansUltraviolet RaysXenopus laevisXenopus ProteinsRNA Polymerase IITranscription Factor TFIIHXenopus ProteinsAlphaFoldcryo-EMNERnucleotide excision repairSTK19TFIIHtranscriptiontranscription-coupled DNA repair

Identifiers

PMID39547228
PMCPMC11645862

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.