Evidence map›Paper›PMID 39546741›Full record

ArticleJCO clinical cancer informatics2024

Serious Games for Serious Pain: Development and Initial Testing of a Cognitive Behavioral Therapy Game for Patients With Advanced Cancer Pain.

Desiree R Azizoddin, Sara M DeForge, Robert R Edwards, Ashton R Baltazar, Kristin L Schreiber, Matthew Allsop, Justice Banson, Gabe Oseuguera, Michael Businelle, James A Tulsky and 1 more

Abstract read
In one paragraph

Article in JCO clinical cancer informatics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Desiree R AzizoddinHealth Promotion Research Center, Stephenson Cancer Center, University of Oklahoma Health Sciences Center, Oklahoma City, OK.ORCID 0000-0001-6993-1776
Sara M DeForgeHealth Promotion Research Center, Stephenson Cancer Center, University of Oklahoma Health Sciences Center, Oklahoma City, OK.
Robert R EdwardsDepartment of Anesthesiology, Perioperative, and Pain Medicine, Brigham and Women's Hospital, Boston, MA.
Ashton R BaltazarHealth Promotion Research Center, Stephenson Cancer Center, University of Oklahoma Health Sciences Center, Oklahoma City, OK.ORCID 0000-0001-9320-6929
Kristin L SchreiberDepartment of Anesthesiology, Perioperative, and Pain Medicine, Brigham and Women's Hospital, Boston, MA.
Matthew AllsopAcademic Unit of Palliative Care, Leeds Institute of Health Sciences, University of Leeds, Leeds, United Kingdom.ORCID 0000-0002-7399-0194
Justice BansonDepartment of Computer Science, Western Washington University, Bellingham, WA.
Gabe OseugueraDepartment of Computer Science, Western Washington University, Bellingham, WA.
Michael BusinelleHealth Promotion Research Center, Stephenson Cancer Center, University of Oklahoma Health Sciences Center, Oklahoma City, OK.ORCID 0000-0002-9038-2238
James A TulskyDepartment of Psychosocial Oncology and Palliative Care, Dana-Farber Cancer Institute, Boston, MA.ORCID 0000-0002-7458-0453
Andrea C EnzingerDivision of Population Sciences, Dana-Farber Cancer Institute, Boston, MA.ORCID 0000-0001-7502-8081

Funding

Tissue Pathology Shared ResourceP30CA225520 · NCI · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI ROBERT S. MANNEL · 2018 to 2026
$27.1M
Integrating pain-CBT into an mHealth analgesic support intervention for patients withchronic pain from advanced cancersK08CA266937 · NCI · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI Desiree R Hilton · 2022 to 2026
$1.0M
Leveraging mHealth to deliver integrated pain-CBT, opioid monitoring, and self-management support for advanced cancer patients coping with chronic painR21CA263838 · NCI · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI AZIZODDIN, DESIREE R · 2022 to 2023
$373k
NCI NIH HHS K08 CA266937NCI NIH HHS L30 CA242493NCI NIH HHS P30 CA225520NCI NIH HHS R21 CA263838
6 · The paper itself

Abstract

purposeCancer-related pain is prevalent among people with advanced cancer. To improve accessibility and engagement with pain-cognitive behavioral therapy (pain-CBT), we developed and tested a serious game hosted within a mobile health intervention that delivers pain-CBT and pharmacologic support. The game focuses on teaching and practicing cognitive restructuring (CR), a central pain-CBT intervention component.

methodsThe pain-CBT game was developed through partnerships with commercial and academic game developers, graphic designers, clinical experts, and patients. Patients with metastatic cancer and pain participated in iterative, semistructured interviews. They described their experience playing each level and reflected on relevance, clarity, usability, and potential changes. Content codes captured patients' suggestions and informed game refinements.

resultsThe final game includes five levels that prompt players to distinguish between adaptive and maladaptive thoughts that are pain- and cancer-specific. The levels vary in objective (eg, hiking and sledding), interaction type (eg, dragging and tapping), and mode of feedback (eg, audio and animation). Fourteen participants reviewed the game. Patients appreciated the pain- and cancer-specific thought examples, with a few noting that the thoughts made them feel less alone. Many stated that the game was fun, relatable, and an engaging distraction. Others noted that the game provided helpful CR practice and prompted reflection. For example, one 40-year-old woman said the game "brings [a thought] to the forefront so you can acknowledge it, and then maybe you could let it go or… do something about it."

conclusionPatients coping with cancer pain found the CR game helpful, enjoyable, and satisfactory. Serious games have the potential to increase engagement while facilitating learning and rehearsal of psychological skills for pain. Future testing will evaluate the efficacy of this serious game.

Indexed as

Cancer PainCognitive Behavioral TherapyPain ManagementVideo GamesAdultAgedFemaleHumansMaleMiddle AgedNeoplasms

Identifiers

PMID39546741
PMCPMC11668515

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.