ArticleMedical physics2025
An energy-conserving dose summation method for dose accumulation in radiotherapy.
Article in Medical physics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
backgroundRadiation therapy often requires the accumulation of doses from multiple treatment fractions or courses for plan evaluation and treatment response assessment. However, due to underlying mass changes, the accumulated dose may not accurately reflect the total deposited energy, leading to potential inaccuracies in characterizing the treatment input. PURPOSE: This study introduces an energy-conserving dose summation method to calculate the total dose in scenarios where patients experience changes in body mass during treatment. METHODS AND MATERIALS: The proposed method transfers dose and mass data from dosimetry images, where the delivered doses were calculated, to a reference image using an energy and mass-conserving dose reconstruction technique. The reconstructed dose assumes the same resolution and dimension as the reference image. The transferred masses are averaged at each image voxel in the reference image to generate an average mass. The transferred doses are then adjusted by multiplying by the ratio of their transferred mass to the average mass, and subsequently summed to calculate a mass-weighted (MW) total dose at each voxel. This method is demonstrated with a case of lung cancer retreatment.
resultsThe MW total dose was shown to be equivalent to the total deposited energy divided by the average mass. In the lung cancer retreatment case, the energy derived from the MW total dose was consistent with the sum of energy transferred from two treatments across all evaluated organs.
conclusionThe MW dose summation method can produce a total dose that accurately reflects the total energy deposited in each organ. The consistency may provide a robust foundation for verifying dose accumulations in adaptive radiotherapy.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.