Evidence map›Paper›PMID 39546456›Full record

ArticlePLOS global public health2024

Uptake and acceptability of oral HIV self-testing in the context of assisted partner services in Western Kenya: A mixed-methods analysis.

Victor Mudhune, Unmesha Roy Paladhi, Mercy Owuor, Kenneth Ngure, David A Katz, George Otieno, Monisha Sharma, Sarah Masyuko, Edward Kariithi, Carey Farquhar and 1 more

Abstract read
In one paragraph

Article in PLOS global public health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Victor MudhuneCentre for Global Health Research, Kenya Medical Research Institute, Kisumu, Kenya.ORCID https://orcid.org/0000-0003-4841-4555
Unmesha Roy PaladhiDepartment of Global Health, University of Washington, Seattle, Washington, United States of America.ORCID https://orcid.org/0000-0001-8147-4782
Mercy OwuorIndependent Qualitative Researcher, Nairobi, Kenya.
Kenneth NgureSchool of Public Health, Jomo Kenyatta University of Agriculture and Technology, Nairobi, Kenya.
David A KatzDepartment of Global Health, University of Washington, Seattle, Washington, United States of America.
George OtienoPATH-Kenya, Kisumu, Kenya.
Monisha SharmaDepartment of Global Health, University of Washington, Seattle, Washington, United States of America.
Sarah MasyukoDepartment of Global Health, University of Washington, Seattle, Washington, United States of America.
Edward KariithiPATH-Kenya, Kisumu, Kenya.
Carey FarquharDepartment of Global Health, University of Washington, Seattle, Washington, United States of America.
Rose BosireCentre for Clinical Research, Kenya Medical Research Institute, Nairobi, Kenya.

Funding

University of Washington/Fred Hutch Center for AIDS ResearchP30AI027757 · NIAID · UNIVERSITY OF WASHINGTON · PI Kenneth Sherr · 1988 to 2026
$104.9M
Promoting Diversity, Equity, and Inclusivity in Research Training to Optimize HIV Prevention and TreatmentD43TW009580 · FIC · UNIVERSITY OF WASHINGTON · PI CAREY FARQUHAR, John Kinuthia · 2013 to 2026
$4.8M
Women and HIV: Translation of Research into Practice-WLHIV Post-Graduate Research FellowshipD43TW009783 · FIC · UNIVERSITY OF WASHINGTON · PI Elizabeth Anne BUKUSI, CAREY FARQUHAR · 2015 to 2026
$4.1M
IMPLEMENTING ASSISTED PARTNER SERVICES TO HIV TEST AND TREAT MEN IN WESTERN KENYAR01AI134130 · NIAID · UNIVERSITY OF WASHINGTON · PI FARQUHAR, CAREY · 2017 to 2021
$3.6M
Global Infectious Diseases and HPV Research Training in KenyaD43TW010905 · FIC · AGA KHAN UNIVERSITY (KENYA) · PI CHUNG, MICHAEL HOONBAE, TEMMERMAN, MARLEEN · 2018 to 2023
$1.2M
Designing an Intervention to Increase Men's Linkage to Care and Prevention after HIV Self-Testing in UgandaK01MH115789 · NIMH · UNIVERSITY OF WASHINGTON · PI SHARMA, MONISHA · 2018 to 2022
$876k
FIC NIH HHS D43 TW009580FIC NIH HHS D43 TW009783FIC NIH HHS D43 TW010905NIAID NIH HHS P30 AI027757NIAID NIH HHS R01 AI134130NIMH NIH HHS K01 MH115789
6 · The paper itself

Abstract

Integrating HIV self-testing (HIVST) into assisted partner services (APS) has potential to increase identification of people with HIV in the community, but little is known about acceptability of HIVST among partners traced via APS. We assessed characteristics of APS partners testing with HIVST, and factors influencing HIVST uptake and acceptability in a cluster-randomized control trial on APS+HIVST. Using convergent parallel mixed-methods design, we evaluated socio-demographic and behavioral characteristics of APS partners who were offered HIVST or provider-delivered testing, and purposively selected a sub-set of partners for in-depth interviews (IDIs). Descriptive and log-binomial regression analyses were performed controlling for health facility clusters, while IDIs were thematically analyzed applying the theoretical framework of acceptability. Among 3312 partners who were offered HIVST or provider-administered testing through APS, 2724 (82.2%) used HIVST. There was no association between partner demographics and HIVST uptake. HIVST use was less likely than provider-delivered testing among those identified as a casual (adjusted relative risk (aRR) = 0.93; 95% Confidence Interval (CI) 0.88-0.98) or transactional (aRR = 0.90; 95% CI 0.87-0.94) partner compared to those in a defined relationship. HIVST use was slightly lower among those offered the option of an additional kit when compared to those only offered one kit (aRR = 0.93; 95% CI 0.88-0.98). In the IDIs (N = 24), partners reported that HIVST was a viable option for individuals who do not find provider-delivered testing suitable or convenient. For the APS partners, 'intervention coherence', 'self-efficacy', and 'ethicality' presented as most significant theoretical framework of acceptability constructs. APS providers played a critical role in creating HIVST awareness and driving acceptability. Increasing HIVST awareness and providing tailored solutions will empower APS clients optimize their HIV testing decisions. Providers should consider context of the partner's sexual encounter and extend counselling support when recommending HIVST within APS.

Identifiers

PMID39546456
PMCPMC11567626

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.