ReviewAdvances in experimental medicine and biology2024
The Cullin-RING Ligase Family in Immune Regulation.
Review in Advances in experimental medicine and biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Cul5: immune cell function and therapeutic potential.Frontiers in immunology · 2026Review
- E3 Ligase Rbx1 Orchestrates Thymus Development and Fate Determination of αβ-γδ T Cells.Research (Washington, D.C.) · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The Cullin-RING ligase (CRL) E3 family is the largest ubiquitin ligase family and consists of a catalytic subunit, a scaffold protein, an adaptor, and a substrate receptor. Each component is different in the different members of the CRL family. CRLs affect the ubiquitination and stability of multiple substrates and regulate many biological processes. In immune regulation, components of CRLs also play critical roles in different types of immune cells and under different physical or pathological conditions. In this review, we summarized the recent advances in research about the functions of CRLs in immune regulation. Different components of the CRL family are associated with the regulation of different immunological processes.
Indexed as
Identifiers
39546136What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.