Evidence map›Paper›PMID 39545993›Full record

ArticleArchives of gynecology and obstetrics2025

Association of body mass index with pathologic agreement of preoperative and postoperative tumor grade in endometrial cancer.

Samantha Taylor, Peter Scalia, Raanan Meyer, Melica Nourmoussavi Brodeur, Shannon Salvador, Susie Lau, Walter Gotlieb, Gabriel Levin

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Article in Archives of gynecology and obstetrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Samantha TaylorDepartment of Obstetrics and Gynecology, McGill University, Montreal, QC, Canada.
Peter ScaliaSchool of Medicine, McGill University, Montreal, QC, Canada.
Raanan MeyerDivision of Minimally Invasive Gynecologic Surgery, Department of Obstetrics and Gynecology, Cedars Sinai Medical Center, Los Angeles, CA, USA.
Melica Nourmoussavi BrodeurDivision of Gynecologic Oncology, Jewish General Hospital, McGill University, Montreal, QC, Canada.
Shannon SalvadorDivision of Gynecologic Oncology, Jewish General Hospital, McGill University, Montreal, QC, Canada.
Susie LauDivision of Gynecologic Oncology, Jewish General Hospital, McGill University, Montreal, QC, Canada.
Walter GotliebDivision of Gynecologic Oncology, Jewish General Hospital, McGill University, Montreal, QC, Canada.
Gabriel LevinDivision of Gynecologic Oncology, Jewish General Hospital, McGill University, Montreal, QC, Canada. gabriel.levin2@mail.mcgill.ca.ORCID 0000-0003-1282-5379

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveWe aim to study association of BMI of EC patients, with the level of agreement between preoperative and postoperative tumor grade.

methodsA retrospective study. We included patients with EC diagnosed in an outpatient clinic which had surgical staging as in our division. We categorized patients into BMI categories according to the World Health Organization; (BMI < 18.5 kg/m

resultsOverall, 623 women met study inclusion criteria, with a median age of 64 [interquartile range (IQR) 57-72]. Among the study cohort, the median BMI was 30.7 [IQR 25.6-38.8], with 330 (53.0%) patients being obese. EC grade 1 was diagnosed preoperatively in 353 (56.7%), grade 3 in 148 (23.8%), and grade 2 in 122 (19.6%). Endometrioid histology was diagnosed in 463 (74.3%), serous in 78 (12.5%), mixed histotype in 51 (8.2%), clear cell in 20 (3.2%) and carcinosarcoma in 11 (1.8%). In 68.7% (n = 428), there was no change in postoperative grade, and in 24.9% (n = 155), there was upgrading of tumor, and in 6.4% (n = 40), there was a tumor downgrade. There were 3 (0.5%) cases in which no tumor was found on final pathology. The rate of no change was higher in preoperative grade 3 (89.9%) vs. grades 1 (63.5%) and grade 2 (58.2%), p < .001). There was no difference in grading agreement when obese patients were compared to non-obese, p = .248. There was no difference in grading agreement when comparing the various BMI categories, with no change proportion ranging between 58.2% in BMI 30.0-34.9 mg/kg

conclusionOur study found no significant association between BMI and the agreement between preoperative and postoperative tumor grading in EC.

Indexed as

Body Mass IndexEndometrial NeoplasmsObesityAgedFemaleHumansMiddle AgedNeoplasm GradingPostoperative PeriodPreoperative PeriodRetrospective StudiesBody mass indexEndometrial biopsyEndometrial carcinomaGradeObesity

Identifiers

PMID39545993
PMCPMC11890242

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.