Evidence map›Paper›PMID 39545647›Full record

ArticleJournal of orthopaedic research : official publication of the Orthopaedic Research Society2025

Inducible displacement of cementless total knee arthroplasty components with conventional and weight-bearing CT-based radiostereometric analysis.

Rebecca A Hext, Bart L Kaptein, James L Howard, Brent A Lanting, Matthew G Teeter

Registry-linked trialAbstract read
In one paragraph

Article in Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06951477 (Gut Microbiome in Orthopaedics), which is not on this map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06951477 not yet recruitingnot on this map

Gut Microbiome in Orthopaedics: Investigating the Role of Gut Microbiome Composition in Total Knee Arthroplasty Failure

TypeobservationalSponsorLondon Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph'sRan2025 to 2027Enrolled30ConditionsRevision Total Knee Arthroplasty, Osteoarthritis, KneeArmsRevision Total Knee Arthroplasty
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Review
  6. Current Uses for Medical Imaging With Orthopaedic Implant Technology.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2026
    Review
  7. Article
  8. Inducible displacement of cementless total knee arthroplasty components with conventional and weight-bearing CT-based radiostereometric analysis.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2025
    Article
  9. Comparison of Marker-Based RSA and CT-RSA for Analyzing Micromotions After Distal Radius Osteotomy: A 1-Year Retrospective Study of 24 Patients.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rebecca A HextDepartment of Medical Biophysics, Schulich School of Medicine & Dentistry, Western University, London, Ontario, Canada.ORCID 0009-0003-4972-8377
Bart L KapteinDepartment of Orthopaedics, Leiden University Medical Center, Leiden, Netherlands.
James L HowardDivision of Orthopaedic Surgery, Schulich School of Medicine & Dentistry, Western University, London, Ontario, Canada.
Brent A LantingDivision of Orthopaedic Surgery, Schulich School of Medicine & Dentistry, Western University, London, Ontario, Canada.
Matthew G TeeterDepartment of Medical Biophysics, Schulich School of Medicine & Dentistry, Western University, London, Ontario, Canada.ORCID 0000-0002-3911-3171

Funding

Stars Career Development Award from the Arthritis Society of Canada 22-053
6 · The paper itself

Abstract

Aseptic loosening remains one of the top causes of revision surgery of total knee arthroplasty (TKA). Radiostereometric analysis (RSA) is used in research to measure implant migration, however limitations prevent its clinical use. New methods have allowed the same measurements as RSA to be performed with computed tomography (CT) scanners (CT-RSA). The objective of this study is to determine inducible displacement measurements from weight-bearing computed tomography (WBCT) and conventional RSA to assess implant stability. Participants (n = 17) completed RSA exams in the supine and standing position, and WBCT exams in the seated (leg extended) and standing position. Double examinations were performed in the seated (WBCT) or supine (RSA) positions. Inducible displacements were measured with model-based RSA (MBRSA) for RSA exams, and a novel CT-RSA software, V3MA, for WBCT exams. Precision of each technique was calculated between double examinations. Precision data for tibial component total translations and rotations were 0.05 mm and 0.118°, respectively with WBCT-RSA, and were 0.108 mm and 0.269°, respectively with MBRSA. MTPM precision was 0.141 mm with WBCT-RSA and was 0.168 mm with MBRSA. Inducible displacement MTPM of the tibial component was 0.244 ± 0.220 mm with WBCT-RSA and 0.662 ± 0.257 mm with MBRSA. Inducible displacement measurements with MBRSA were significantly different from WBCT-RSA for tibial component anterior tilt (p = 0.0002). WBCT-RSA demonstrated comparable precision to MBRSA, and both techniques measured inducible displacements consistent with stable components. Clinical Significance: As the availability of WBCT increases, its use as an alternative to MBRSA is supported to measure the instantaneous fixation of implant components.

Indexed as

Arthroplasty, Replacement, KneeKnee ProsthesisRadiostereometric AnalysisTomography, X-Ray ComputedAgedAged, 80 and overFemaleHumansMaleMiddle AgedProsthesis FailureWeight-Bearingimplant fixationinducible displacementweight‐bearing computed tomography

Identifiers

PMID39545647
PMCPMC11806650

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.