Evidence map›Paper›PMID 39545198›Full record

ArticleOpen veterinary journal2024

Stem bark ethanolic extract of

Agung Budianto Achmad, Annise Proboningrat, Arif Nur Muhammad Ansori, Amaq Fadholly, Siti Eliana Rochmi, Rinza Rahmawati Samsudin, Nanik Hidayatik, Gracia Angelina Hendarti, Shara Jayanti

Abstract read
In one paragraph

Article in Open veterinary journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Stilbene Glycosides inPlants (Basel, Switzerland) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Agung Budianto AchmadDepartment of Health, Faculty of Vocational Studies, Universitas Airlangga, Surabaya, Indonesia.
Annise ProboningratDivision of Veterinary Pathology, Faculty of Veterinary Medicine, Universitas Airlangga, Surabaya, Indonesia.
Arif Nur Muhammad AnsoriPostgraduate School, Universitas Airlangga, Surabaya, Indonesia.
Amaq FadhollyDivision of Pharmacology and Toxicology, School of Veterinary and Biomedical Medicine, IPB University, Bogor, Indonesia.
Siti Eliana RochmiDepartment of Health, Faculty of Vocational Studies, Universitas Airlangga, Surabaya, Indonesia.
Rinza Rahmawati SamsudinDepartment of Chemistry, Faculty of Health Sciences, Muhammadiyah University of Surabaya, Surabaya, Indonesia.
Nanik HidayatikDivision of Basic Veterinary Medicine, Faculty of Veterinary Medicine, Universitas Airlangga, Surabaya, Indonesia.
Gracia Angelina HendartiDivision of Veterinary Anatomy, Faculty of Veterinary Medicine, Universitas Airlangga, Surabaya, Indonesia.
Shara JayantiMarine and Fisheries Polytechnic, Surabaya, Indonesia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Cervical cancer is a severe concern for women throughout the world. This percentage of cancer incidence causes sufferers to die at a high rate. It is believed that the bark of the Aim: This present study aims to examine the cytotoxic ability of Methods: We administered the PMBE at concentrations of 50, 100, 200, and 400 µg/ml to HeLa cell cultures. We then conducted the MTT cytotoxicity assay, detected apoptosis via Annexin V binding, and observed caspase 9 expression via immunocytochemistry. Results: PMBE showed cytotoxic activity on HeLa cells with an IC Conclusion: Based on this study, PMBE is predicted to have dose-dependent antiproliferative or cytotoxicity effects on the HeLa cell line through the intrinsic pathway apoptosis mechanism.

Indexed as

ApoptosisCaspase 9PinusPlant BarkPlant ExtractsFemaleHeLa CellsHumansUterine Cervical NeoplasmsCaspase 9Plant ExtractsAnticancerApoptosisCervical cancerPinaceae

Identifiers

PMID39545198
PMCPMC11560255

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.