Evidence map›Paper›PMID 39545060›Full record

ArticleFrontiers in pharmacology2024

First case report of a vertebral osteomyelitis caused by carbapenem-resistant

Paul Laffont-Lozes, Tayma Naciri, Alix Pantel, Aurélie Martin, Anne-Sophie Pruvot-Occean, Vincent Haignere, Paul Loubet, Albert Sotto, Romaric Larcher

Abstract read
In one paragraph

Article in Frontiers in pharmacology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Paul Laffont-LozesDepartment of Pharmacy, Nimes University Hospital, Nîmes, France.
Tayma NaciriDepartment of Infectious and Tropical Diseases, Nimes University Hospital, Nîmes, France.
Alix PantelDepartment of Microbiology and Hospital Hygiene, Nimes University Hospital, Nîmes France.
Aurélie MartinDepartment of Infectious and Tropical Diseases, Nimes University Hospital, Nîmes, France.
Anne-Sophie Pruvot-OcceanDepartment of Neurosurgery, Nimes University Hospital, Nîmes, France.
Vincent HaignereDepartment of Orthopaedic Surgery and Traumatology, Nimes University Hospital, Nîmes, France.
Paul LoubetDepartment of Infectious and Tropical Diseases, Nimes University Hospital, Nîmes, France.
Albert SottoDepartment of Infectious and Tropical Diseases, Nimes University Hospital, Nîmes, France.
Romaric LarcherDepartment of Infectious and Tropical Diseases, Nimes University Hospital, Nîmes, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Bone and joint infections (BJIs) caused by multidrug-resistant bacteria are becoming more frequent. However, data on the use of novel β-lactam/β-lactamase inhibitors, such as imipenem/cilastatin/relebactam (I-R) and meropenem/vaborbactam (MVB), to treat BJIs is lacking. Furthermore, prolonged infusions of these β-lactams should theoretically optimize pharmacokinetic/pharmacodynamics target in these indications, but there are currently no reports on this type of infusions, especially in the setting of BJI. Case Presentation: We report a case of a vertebral osteomyelitis caused by carbapenem-resistant Conclusion: The favourable outcome of this patient treated for a vertebral osteomyelitis caused by carbapenem-resistant

Indexed as

bone and joint infectioncontinuous infusionextended infusionimipenem/cilastatin/relebactammeropenem/vaborbactamtherapeutic drug monitoringvertebral osteomyelitis

Identifiers

PMID39545060
PMCPMC11561750

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.