Evidence map›Paper›PMID 39545044›Full record

ArticleFrontiers in nutrition2024

Modulating the gut microbiota in Crohn's disease: a pilot study on the impact of a plant-based diet with DNA-based monitoring.

Stine Karstenskov Østergaard, Zeynep Cetin, Henrik Højgaard Rasmussen, Helle Nygaard Lærke, Mette Holst, Charlotte Lauridsen, Jeppe Lund Nielsen

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in nutrition, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Stine Karstenskov ØstergaardDepartment of Chemistry and Bioscience, Aalborg University, Aalborg, Denmark.
Zeynep CetinDepartment of Gastroenterology and Hepatology, Center for Nutrition and Intestinal Failure, Aalborg University Hospital, Aalborg, Denmark.
Henrik Højgaard RasmussenDepartment of Gastroenterology and Hepatology, Center for Nutrition and Intestinal Failure, Aalborg University Hospital, Aalborg, Denmark.
Helle Nygaard LærkeDepartment of Animal and Veterinary Sciences, Aarhus University, Foulum, Denmark.
Mette HolstDepartment of Gastroenterology and Hepatology, Center for Nutrition and Intestinal Failure, Aalborg University Hospital, Aalborg, Denmark.
Charlotte LauridsenDepartment of Clinical Medicine, Aalborg University, Aalborg, Denmark.
Jeppe Lund NielsenDepartment of Chemistry and Bioscience, Aalborg University, Aalborg, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Crohn's Disease (CD) is characterized by chronic intestinal inflammation and dysbiosis. This study aimed to investigate the effects of a plant-based diet (PBD) on gut microbiota composition and inflammation in CD patients and assess the utility of Methods: Fourteen CD patients participated in a 12-week PBD intervention. Dietary adherence was monitored through self-reported food diaries and trnL sequencing, which detects plant residues in fecal samples. Gut microbiota was analyzed using 16S rRNA sequencing, and fecal calprotectin levels were measured as an indicator of intestinal inflammation. Results: Discussion: A PBD positively influenced gut microbiota composition and decreased intestinal inflammation in CD patients. The study also demonstrated that

Indexed as

16S rRNACrohns diseasediet interventionDNA-based dietary monitoringplant-based dietTRNL

Identifiers

PMID39545044
PMCPMC11560762

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.