Evidence map›Paper›PMID 39544953›Full record

ArticleCureus2024

Long-Term Suboptimal Anticoagulation in a Patient With Double Mechanical Heart Valves Leading to Stroke and Heart Failure.

Gurvinder Sidhu, Pratyush Pradeep, Dyutima Singh, Bara Erhayiem

Abstract readCase Reports
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Gurvinder SidhuCardiology, Nottingham University Hospitals National Health Service (NHS) Trust, Nottingham, GBR.
Pratyush PradeepInternal Medicine, Calderdale and Huddersfield National Health Service (NHS) Foundation Trust, Huddersfield, GBR.
Dyutima SinghCardiology, Nottingham University Hospitals National Health Service (NHS) Trust, Nottingham, GBR.
Bara ErhayiemCardiology, Nottingham University Hospitals National Health Service (NHS) Trust, Nottingham, GBR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mechanical heart valve replacements are highly durable and effective but come with a substantial requirement for lifelong anticoagulation therapy to prevent thromboembolic complications. Unlike biological valve replacements, which typically require less rigorous anticoagulation, mechanical valves - particularly in the aortic and mitral positions - present a higher risk for clot formation, necessitating strict adherence to anticoagulation regimens. This case report examines a 59-year-old male with double mechanical heart valve replacements who experienced poor compliance with anticoagulation therapy for over 30 years, ultimately leading to significant health complications. Despite his long-standing non-compliance, the patient initially avoided severe thromboembolic events until he suffered a stroke in 2022, followed by the onset of severe heart failure due to persistent suboptimal anticoagulation. His case is unique, given the prolonged lack of adherence to anticoagulation therapy, and highlights the critical need for consistent anticoagulation management in patients with mechanical heart valves. We explore the challenges of managing anticoagulation in complex cases and underscore the importance of consistent adherence to anticoagulation therapy, multidisciplinary intervention, and patient education in improving patient outcomes.

Indexed as

heart failure with reduced ejection fractionmechanical heart valvesoral anticoagulationstrokesurgical case reports

Identifiers

PMID39544953
PMCPMC11563460

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.