ArticleAmerican journal of translational research2024
Effect of Er:YAG laser combined with minocycline hydrochloride on inflammatory response in patients with combined endodontal-periodontal lesions.
Article in American journal of translational research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Effects of Xipayi Gingival Solution combined with minocycline hydrochloride on inflammatory cytokines and masticatory function in patients with chronic periodontitis.Frontiers in cellular and infection microbiology · 2026Trial
- The dynamic elimination effect of local adjuvant therapy on the periodontal microbiota.Journal of oral microbiology · 2026Article
- Effectiveness of the Er:YAG Laser in Snoring Treatment Based on Systematic Review and Meta-Analysis Results.Journal of clinical medicine · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo evaluate the efficacy of Erbium-doped: yttrium-aluminum garnet (Er:YAG) laser combined with minocycline hydrochloride (Mino-HCL) in treating combined endodontal-periodontal lesions (CEPLs), and to provide a clinical reference for its use.
methodsA total of 114 patients with CEPLs, admitted to Aerospace Center Hospital from October 2021 to October 2023, were retrospectively analyzed. Of these, 53 patients were treated with Er:YAG laser (control group) and 61 patients received Er:YAG laser combined with Mino-HCL (research group). Clinical efficacy and pain severity were compared between the two groups. Measurements included plaque index (PLI), sulcus bleeding index (SBI), probing depth (PD), inflammatory factors, and oxidative stress, with adverse effects recorded. A 6-month follow-up assessed the quality of life and oral health outcomes in both groups.
resultsThe research group demonstrated superior clinical efficacy, reduced pain, and improved management of inflammatory responses and oxidative stress compared to the control group (all P<0.05). Additionally, the research group had lower SBI, PLI, and PD values post-treatment (all P<0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P>0.05). Follow-up results indicated better quality of life and oral health in the research group.
conclusionThe combination of Er:YAG laser and Mino-HCL is effective for treating CEPLs.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.