Evidence map›Paper›PMID 39544550›Full record

ArticleCureus2024

Eco-Friendly Synthesis of Cerium Nanoparticles Using Spirulina platensis: Assessing Antibacterial and Anti-inflammatory Efficacy.

Mathesh A, Ramanathan Snega, P Geetha Sravanthy, Muthupandian Saravanan

Abstract read
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mathesh ADepartment of Pharmacology, Antimicrobial Resistance (AMR) and Nanotherapeutics Lab, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences (SIMATS), Chennai, IND.
Ramanathan SnegaDepartment of Pharmacology, Antimicrobial Resistance (AMR) and Nanotherapeutics Lab, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences (SIMATS), Chennai, IND.
P Geetha SravanthyDepartment of Pharmacology, Antimicrobial Resistance (AMR) and Nanotherapeutics Lab, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences (SIMATS), Chennai, IND.
Muthupandian SaravananDepartment of Pharmacology, Antimicrobial Resistance (AMR) and Nanotherapeutics Lab, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences (SIMATS), Chennai, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introduction

objectiveThis study aimed to utilize METHODOLOGY:

resultThe green synthesis of cerium oxide nanoparticles (CeO-NPs) using Spirulina, a sustainable and eco-friendly method has potential application in antibacterial and anti-inflammatory therapies. This study focuses on the green synthesis of CeO-NPs and characterizes them by using UV-Vis, Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction analysis (XRD), SEM, and EDX. The UV-vis analysis confirmed the presence of CeO-NPs at a wavelength of 320 nm. FT-IR reveals four functional groups, such as C-O, N-O, and C=C stretches. XRD analysis showed higher crystalline and less amorphous content. SEM and EDX spectra were utilized to confirm the morphology (agglomerated square shape) and the elemental composition [Ce, O, C] in the CeO-NPs. The antibacterial activity was evaluated against multidrug-resistant (MDR) clinical strains and the anti-inflammatory activity revealed significant activity in a dose-dependent manner.

conclusionThis study concluded that Spirulina-mediated CeO-NPs have potential as a drug in biomedical assays. Further in vitro and in vivo analysis is required to fully confirm their viability as a potential drug.

Indexed as

antibacterial activityanti-inflammatoryceo-npsenvironmental friendlygreen synthesisspirulina

Identifiers

PMID39544550
PMCPMC11561378

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.