Evidence map›Paper›PMID 39544517›Full record

ArticleApplied soft computing2021

Ensemble-learning regression to estimate sleep apnea severity using at-home oximetry in adults.

Gonzalo C Gutiérrez-Tobal, Daniel Álvarez, Fernando Vaquerizo-Villar, Andrea Crespo, Leila Kheirandish-Gozal, David Gozal, Félix Del Campo, Roberto Hornero

Abstract read
In one paragraph

Article in Applied soft computing, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Nocturnal blood pressure burden: towards a better understanding of the OSA-hypertension relationship.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Gonzalo C Gutiérrez-TobalBiomedical Engineering Group, Universidad de Valladolid, Valladolid, Spain.
Daniel ÁlvarezBiomedical Engineering Group, Universidad de Valladolid, Valladolid, Spain.
Fernando Vaquerizo-VillarBiomedical Engineering Group, Universidad de Valladolid, Valladolid, Spain.
Andrea CrespoBiomedical Engineering Group, Universidad de Valladolid, Valladolid, Spain.
Leila Kheirandish-GozalDepartment of Child Health, and the Child Health Research Institute, The University of Missouri School of Medicine, Columbia, Missouri, USA.
David GozalDepartment of Child Health, and the Child Health Research Institute, The University of Missouri School of Medicine, Columbia, Missouri, USA.
Félix Del CampoBiomedical Engineering Group, Universidad de Valladolid, Valladolid, Spain.
Roberto HorneroBiomedical Engineering Group, Universidad de Valladolid, Valladolid, Spain.

Funding

National Sleep Research Resource (NSRR)R24HL114473 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI REDLINE, SUSAN S., ZHANG, GUO-QIANG · 2013 to 2017
$7.5M
DATA COORDINATING CENTER FOR SLEEP HEART STUDYU01HL064360 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI DIENER-WEST, MARIE · 1999 to 2007
$4.4M
APP-mediated signaling, sleep perturbations, and Alzheimer's disease mouse modelsRF1AG061824 · NIA · UNIVERSITY OF SOUTH FLORIDA · PI GOZAL, DAVID, PARENT, ANGELE · 2019 to 2019
$3.5M
HL - Exosomes, Blood, Brain Barrier, and Cognitive Function in Pediatric OSAR01HL130984 · NHLBI · UNIVERSITY OF MISSOURI-COLUMBIA · PI GOZAL, LEILA KHEIRANDISH · 2016 to 2020
$3.5M
THE SLEEP HEART HEALTH STUDY: READING CENTER APPLICATIONU01HL063463 · NHLBI · CASE WESTERN RESERVE UNIVERSITY · PI REDLINE, SUSAN S. · 1999 to 2007
$2.8M
The Sleep Heart Health Study (SHHS)U01HL053938 · NHLBI · UNIVERSITY OF ARIZONA · PI QUAN, STUART F. · 1994 to 2007
$2.0M
SLEEP HEART HEALTH STUDYU01HL053931 · NHLBI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI RAPOPORT, DAVID M. · 1994 to 2003
$1.9M
THE SLEEP HEART HEALTH STUDYU01HL053937 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI PUNJABI, NARESH · 1994 to 2007
$1.6M
SLEEP HEART HEALTH STUDYU01HL053916 · NHLBI · UNIVERSITY OF CALIFORNIA DAVIS · PI ROBBINS, JOHN A · 1994 to 2007
$1.5M
THE SLEEP HEART HEALTH STUDYU01HL053934 · NHLBI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI SHAHAR, EYAL · 1994 to 2007
$1.4M
SLEEP HEART HEALTH STUDYU01HL053941 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI O'CONNOR, GEORGE T · 1994 to 2007
$1.4M
Plasma Exosomes and Vascular Dysfunction in Adults with Sleep ApneaR56HL140548 · NHLBI · UNIVERSITY OF MISSOURI-COLUMBIA · PI GOZAL, DAVID · 2018 to 2018
$794k
NHLBI NIH HHS R01 HL130984NHLBI NIH HHS R24 HL114473NHLBI NIH HHS R56 HL140548NHLBI NIH HHS U01 HL053916NHLBI NIH HHS U01 HL053931NHLBI NIH HHS U01 HL053934NHLBI NIH HHS U01 HL053937NHLBI NIH HHS U01 HL053938NHLBI NIH HHS U01 HL053941NHLBI NIH HHS U01 HL063463NHLBI NIH HHS U01 HL064360NIA NIH HHS RF1 AG061824
6 · The paper itself

Abstract

Overnight pulse oximetry has shown usefulness to simplify obstructive sleep apnea (OSA) diagnosis when combined with machine-learning approaches. However, the development and evaluation of a single model with ability to reach high diagnostic performance in both community-based non-referral and clinical referral cohorts are still pending. Since ensemble-learning algorithms are known for their generalization ability, we propose a least-squares boosting (LSBoost) model aimed at estimating the apnea-hypopnea index (AHI), as the correlate clinical measure of disease severity. A thorough characterization of 8,762 nocturnal blood-oxygen saturation signals (SpO

Indexed as

decision curve analysisensemble learningoximetrySleep apneaSleep Heart Health Study

Identifiers

PMID39544517
PMCPMC11563155

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.