Evidence map›Paper›PMID 39544449›Full record

ArticleCase reports in critical care2024

Hemophagocytic Lymphohistiocytosis Presenting With ARDS in a Young Adult: A Case Report.

Zehra Dhanani, Stephen Dachert

Abstract readCase Reports
In one paragraph

Article in Case reports in critical care, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Zehra DhananiThoracic Medicine and Surgery, Temple University Hospital, Philadelphia, Pennsylvania, USA.ORCID https://orcid.org/0009-0008-7274-3061
Stephen DachertThoracic Medicine and Surgery, Lewis Katz School of Medicine at Temple University, Philadelphia, Pennsylvania, USA.ORCID https://orcid.org/0000-0002-5612-0904

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fever is common in the ICU, with infectious causes accounting for only half of febrile episodes. This case examines a young male who developed high-grade fevers and pulmonary infiltrates unresponsive to broad-spectrum antibiotics. Examination revealed hepatosplenomegaly, hypertriglyceridemia, anemia, and thrombocytopenia, suggestive of hemophagocytic lymphohistiocytosis (HLH). Meeting 5 of 8 HLH criteria, high-dose steroids were administered, resulting in clinical improvement. HLH, with a high mortality risk, demands early recognition, complicated by nonspecific symptoms. This case highlights the rare manifestation of ARDS in HLH, adding diagnostic challenges in critical care settings.

Indexed as

ARDScase reportfebrile illnessintensive care unit

Identifiers

PMID39544449
PMCPMC11563708

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.