Evidence map›Paper›PMID 39544415›Full record

ArticleChemCatChem2024

Electrochemical Non-Directed Arene C-H Amination.

Griffin Stewart, Chris Rapala, Christian A Malapit

Abstract read
In one paragraph

Article in ChemCatChem, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Griffin StewartDepartment of Chemistry, Northwestern University, Technological Institute, Evanston IL 60208.
Chris RapalaDepartment of Chemistry, Northwestern University, Technological Institute, Evanston IL 60208.
Christian A MalapitDepartment of Chemistry, Northwestern University, Technological Institute, Evanston IL 60208.

Funding

Electrocatalysis for the synthesis of chiral and PET imaging pharmaceuticalsR00GM140249 · NIGMS · NORTHWESTERN UNIVERSITY · PI MALAPIT, CHRISTIAN · 2022 to 2024
$747k
NIGMS NIH HHS R00 GM140249
6 · The paper itself

Abstract

Electrosynthesis represents a dynamic field in organic chemistry for the development of important and selective reactions. Among the most interesting electrosynthetic transformations is the non-directed arene C-H amination. Despite increasing reports, the quest for a non-directed electrochemical arene C-H amination capable of accommodating a wide range of arenes and amines with high site-selectivity remains ongoing. Non-directed electrochemical C-H amination presents a metal-free, mild approach for synthesizing complex aminated compounds of interest in pharmaceuticals and natural products. This concept aims to introduce the concept of non-directed electrochemical C-H amination and provide an overview of the recent advances in the field as well as the current limitations and potential directions.

Indexed as

aminationaryl aminesC–H functionalizationelectrosynthesisnitrogen radicals

Identifiers

PMID39544415
PMCPMC11562937

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.