Reply to the letter to the editor entitled "Bridging the species divide: The limits of rat models in capturing human PVOD mechanisms" by Perros F. et al.
Amit Prabhakar, Rahul Kumar, Meetu Wadhwa, Rubin M Tuder, Nicholas W Morrell, Brian B Graham, Giorgio Lagna, Akiko Hata
Article in Pulmonary circulation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
8 authors.
Amit PrabhakarCardiovascular Research Institute, University of California San Francisco California USA.
Rahul KumarLung Biology Center, Pulmonary and Critical Care Medicine, Zuckerberg San Francisco General Hospital San Francisco California USA.
Meetu WadhwaDepartment of Radiology University of California San Francisco California USA.
Rubin M TuderDepartment of Medicine University of Colorado School of Medicine Aurora Colorado USA.
Nicholas W MorrellDepartment of Medicine Victor Phillip Dahdaleh Heart & Lung Research Institute, University of Cambridge Cambridge UK.
Brian B GrahamLung Biology Center, Pulmonary and Critical Care Medicine, Zuckerberg San Francisco General Hospital San Francisco California USA.ORCID 0000-0001-7541-2585
Giorgio LagnaCardiovascular Research Institute, University of California San Francisco California USA.
Akiko HataCardiovascular Research Institute, University of California San Francisco California USA.ORCID 0000-0003-3784-1738
Funding
VRAC and Rho in pulmonary EC proliferationP01HL014985 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI STENMARK, KURT R. · 1985 to 2019
$35.1M
Role of Complement-Driven Pulmonary Vascular Inflammation in PHP01HL152961 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI DELANEY, CASSIDY A · 2020 to 2024
$14.1M
Investigating paclitaxel treatment in a pre-clinical model of Schistosoma-pulmonary hypertensionR01HL135872 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI Brian Barkley Graham · 2017 to 2026
$5.1M
Elucidating the structural insights into the BMP receptor mutations in PAHR01HL164581 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Akiko Hata, Natalia Jura · 2023 to 2026
$3.1M
Molecular pathogenesis of pulmonary arterial hypertensionR01HL153915 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HATA, AKIKO · 2021 to 2024
$3.1M
Identification of a novel modulator of Pulmonary Artery HypertensionR01HL132058 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HATA, AKIKO · 2016 to 2019
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Reply to the letter to the editor entitled "Bridging the species divide: The limits of rat models in capturing human PVOD mechanisms" by Perros F. et al. · full record | OpenQuestion