Evidence map›Paper›PMID 39544193›Full record

ArticlePulmonary circulation2024

The metabolic and physiologic impairments underlying long COVID associated exercise intolerance.

Brooks P Leitner, Phillip Joseph, Andres Figueroa Quast, Maria Alejandra Ramirez, Paul M Heerdt, Jose G Villalobos, Inderjit Singh

Abstract read
In one paragraph

Article in Pulmonary circulation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Observational
  4. Vascular inflammation in neuropsychiatric long COVID.Brain, behavior, & immunity - health · 2026
    Article
  5. Article
  6. Article
  7. Bridging Gaps in Long COVID Therapy: A Review.Current medicinal chemistry · 2026
    Review
  8. Article
  9. Native T1 is independently associated with aerobic exercise capacity in long-term follow-up after mild initial COVID-19 disease (Impression COVID&Heart Study).Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Brooks P LeitnerYale School of Medicine New Haven Connecticut USA.
Phillip JosephDepartment of Medicine, Section of Pulmonary, Critical Care, and Sleep Medicine Yale School of Medicine New Haven Connecticut USA.ORCID 0000-0001-9299-8629
Andres Figueroa QuastDepartment of Medicine, Section of Pulmonary, Critical Care, and Sleep Medicine Yale School of Medicine New Haven Connecticut USA.
Maria Alejandra RamirezDepartment of Medicine, Section of Pulmonary, Critical Care, and Sleep Medicine Yale School of Medicine New Haven Connecticut USA.
Paul M HeerdtDepartment of Anesthesiology Yale School of Medicine New Haven Connecticut USA.
Jose G VillalobosDepartment of Medicine, Section of Pulmonary, Critical Care, and Sleep Medicine Yale School of Medicine New Haven Connecticut USA.
Inderjit SinghDepartment of Medicine, Section of Pulmonary, Critical Care, and Sleep Medicine Yale School of Medicine New Haven Connecticut USA.ORCID 0000-0001-5624-1274

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
NCATS NIH HHS UL1 TR001863
6 · The paper itself

Abstract

Data from invasive CPET (iCPET) revealed long COVID patients have impaired systemic oxygen extraction (EO

Indexed as

invasive CPETlong COVIDmetabolomicPASC

Identifiers

PMID39544193
PMCPMC11560803

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.