Evidence map›Paper›PMID 39544184›Full record

ReviewJournal of biological methods2024

The development and application of cleavage under targets and tagmentation (CUT&Tag) technology.

Chaoyang Xiong, Jiyin Wang, Xinglin Li, Guohong Li, Xi Wang

Abstract readReview
In one paragraph

Review in Journal of biological methods, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Regulation Ratio: A Singular Multi-Omic Measurement of Gene Regulatory Mechanisms.Computational and structural biotechnology journal · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Chaoyang XiongBeijing Key Laboratory of Emerging Infectious Diseases, Institute of Infectious Diseases, Beijing Ditan Hospital, Capital Medical University, Beijing, China.
Jiyin WangBeijing Key Laboratory of Emerging Infectious Diseases, Institute of Infectious Diseases, Beijing Ditan Hospital, Capital Medical University, Beijing, China.
Xinglin LiBeijing Key Laboratory of Emerging Infectious Diseases, Institute of Infectious Diseases, Beijing Ditan Hospital, Capital Medical University, Beijing, China.
Guohong LiHubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Wuhan University, Wuhan, China.
Xi WangBeijing Key Laboratory of Emerging Infectious Diseases, Institute of Infectious Diseases, Beijing Ditan Hospital, Capital Medical University, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The regulation of chromatin structure and gene transcription in eukaryotic cells is an involved process mediated by histone modifications, chromatin-binding proteins, and transcription factors. Studying the distribution of histone modifications and transcription factors at the whole-genome level is crucial for understanding the mechanisms of gene transcription. Cleavage under targets and tagmentation (CUT&Tag) is a novel chromatin analysis method that has rapidly gained popularity in the field of epigenetics since its introduction. It has been widely used for the detection of chromatin modifications and transcription factors in different species. Furthermore, CUT&Tag has also been adapted to simultaneously detect multiple epigenetic modifications. Its integration with single-cell transcriptome, and spatial transcriptome analysis allows for a comprehensive examination of cell fate and functions. In this review, we aimed to provide an overview of the recent developments and applications of CUT&Tag and its derivatives, highlighting their significance in advancing our understanding of epigenetic regulation.

Indexed as

Cleavage under targets and tagmentationEpigeneticHistone modification

Identifiers

PMID39544184
PMCPMC11557298

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.