Evidence map›Paper›PMID 39544019›Full record

ArticlePediatrics2024

Hepatitis C Virus Testing Among Perinatally Exposed Children: 2018 to 2020.

Kate R Woodworth, Samantha Distler, Daniel J Chang, Jackie Luong, Suzanne Newton, Amanda Akosa, Lauren Orkis, Bethany Reynolds, Cynthia Carpentieri, Teri Willabus and 7 more

Abstract read
In one paragraph

Article in Pediatrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

17 authors.

Kate R WoodworthDivision of Birth Defects and Infant Disorders, National Center on Birth Defects and Developmental Disabilities.
Samantha DistlerG2S Corporation, San Antonio, Texas.
Daniel J ChangG2S Corporation, San Antonio, Texas.
Jackie LuongDivision of Birth Defects and Infant Disorders, National Center on Birth Defects and Developmental Disabilities.
Suzanne NewtonDivision of Birth Defects and Infant Disorders, National Center on Birth Defects and Developmental Disabilities.
Amanda AkosaDivision of Birth Defects and Infant Disorders, National Center on Birth Defects and Developmental Disabilities.
Lauren OrkisPennsylvania Department of Health, Pittsburgh, Pennsylvania.
Bethany ReynoldsPennsylvania Department of Health, Pittsburgh, Pennsylvania.
Cynthia CarpentieriGeorgia Department of Health, Atlanta, Georgia.
Teri WillabusGeorgia Department of Health, Atlanta, Georgia.
Anthony OsinskiMassachusetts Department of Health, Boston, Massachusetts.
Hanna ShephardMassachusetts Department of Health, Boston, Massachusetts.
Umme-Aiman HalaiLos Angeles County Department of Health, Los Angeles, California.
Caleb LyuLos Angeles County Department of Health, Los Angeles, California.
Lindsey SizemoreDivision of Viral Hepatitis, National Center for HIV, Viral Hepatitis, STD, and Tuberculosis Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia.
Amy SandulDivision of Viral Hepatitis, National Center for HIV, Viral Hepatitis, STD, and Tuberculosis Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia.
Van T TongDivision of Birth Defects and Infant Disorders, National Center on Birth Defects and Developmental Disabilities.

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

objectiveTo assess the frequency of hepatitis C virus (HCV) testing among a population-based cohort of perinatally exposed children and identify factors associated with testing.

methodsUsing a population-based surveillance cohort of perinatally exposed children born from 2018 to 2020 from 4 US jurisdictions (Georgia; Massachusetts; Allegheny County, Pennsylvania; and Los Angeles County, California), we describe the frequency, timing, and type of HCV testing among children and identify characteristics associated with having an HCV test result by the age of 2 to 3 years. Data were obtained from electronic laboratory reporting, vital records, and medical records.

resultsOf 803 perinatally exposed children, 7 (1%) died before the age of 24 months. Of 796 children, health departments were unable to find medical records or laboratory reports for 181 (23%). Among those with medical record abstraction at 24 months or testing reported before the age of 3 years (n = 615), 50% had an HCV test. The majority (70% of those tested) were tested for HCV antibodies at the age of 18 months or later, although 9% had an HCV nucleic acid test at ages 2 to <6 months. No characteristics examined were found to be significantly associated with having testing reported.

conclusionsIn this surveillance report, we identify the gaps in current testing among children perinatally exposed to hepatitis C. Provider education and resources for health departments for follow-up and linkage to care can improve the identification of children requiring treatment, a vital piece of HCV elimination.

Indexed as

Hepatitis CInfectious Disease Transmission, VerticalChild, PreschoolCohort StudiesFemaleHepacivirusHepatitis C AntibodiesHumansInfantInfant, NewbornMalePregnancyPregnancy Complications, InfectiousUnited StatesHepatitis C Antibodies

Identifiers

PMID39544019
PMCPMC11647573

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.