Evidence map›Paper›PMID 39543997›Full record

ArticleAnimal bioscience2025

Influence of hormonal treatments on progesterone levels to enhance embryo survival and kidding rates in goats.

Manita Wittayarat, Navapol Kupthammasan, Hakim Jehdo, Ratree Jintana, Sopita Suttikrai, Niraporn Tongkumtae, Nantarat Chutijiratthitkan, Pokchon Khirilak, Sirirat Norsoongnern, Supitcha Kaewma and 2 more

Abstract read
In one paragraph

Article in Animal bioscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Manita WittayaratFaculty of Veterinary Science, Prince of Songkla University, Songkhla, Thailand.
Navapol KupthammasanFaculty of Veterinary Science, Prince of Songkla University, Songkhla, Thailand.
Hakim JehdoSmall Ruminant Research and Development Center, Faculty of Natural Resources, Prince of Songkla University, Songkhla, Thailand.
Ratree JintanaResearch and Development Center for Livestock Production Technology, Animal Hospital and Student Training Center, Faculty of Veterinary Science, Chulalongkorn University, Nakhon Pathom, Thailand.
Sopita SuttikraiResearch and Development Center for Livestock Production Technology, Animal Hospital and Student Training Center, Faculty of Veterinary Science, Chulalongkorn University, Nakhon Pathom, Thailand.
Niraporn TongkumtaeSongkhla Artificial Insemination and Biotechnology Research Center, Department of Livestock Development, Songkhla, Thailand.
Nantarat ChutijiratthitkanFaculty of Veterinary Science, Prince of Songkla University, Songkhla, Thailand.
Pokchon KhirilakFaculty of Veterinary Science, Prince of Songkla University, Songkhla, Thailand.
Sirirat NorsoongnernSmall Ruminant Research and Development Center, Faculty of Natural Resources, Prince of Songkla University, Songkhla, Thailand.
Supitcha KaewmaFaculty of Veterinary Science, Prince of Songkla University, Songkhla, Thailand.
Chaiyawan WattanachantSmall Ruminant Research and Development Center, Faculty of Natural Resources, Prince of Songkla University, Songkhla, Thailand.
Saritvich PanyaboribanFaculty of Veterinary Science, Prince of Songkla University, Songkhla, Thailand.

Funding

National Research Council of Thailand N24A650557National Science, Research and Innovation FundPrince of Songkla University VET6701044S-1
6 · The paper itself

Abstract

objectiveThis study investigated the efficiency of different estrous synchronization programs and hormonal treatments in improving reproductive outcomes in goats. Conducted on a commercial farm in southern Thailand, the study used multiparous Shami and Anglo-Nubian breed goats.

methodsIn experiment 1, goats were randomly allocated to two estrous synchronization treatments: 11-day (CI11D) and 13-day (CI13D) intravaginal progesterone implants, followed by artificial insemination (AI) with frozen-thawed semen. Various hormonal treatments (human chorionic gonadotropin [hCG], gonadotropin-releasing hormone [GnRH] analogue, progestogen) were administered on day 5 post-AI to elevate progesterone levels. Experiment 2 assessed embryo survival after transferring early- and late-stage embryos, using GnRH analogue to increase progesterone levels in the recipient goats.

resultsResults showed that GnRH analogue significantly increased pregnancy rates, kidding rates, and the number of kids born in the CI13D group. Progesterone levels were higher in treated groups, particularly with GnRH analogue, though estradiol levels varied between synchronization protocols. Late-stage embryo transfers significantly improved pregnancy rates and reduced embryonic loss compared to early-stage transfers. GnRH analogue supplementation reduced early embryonic mortality, enhancing embryo survival and overall reproductive performance.

conclusionThis study demonstrates the efficacy of tailored estrous synchronization and hormonal treatments in optimizing goat reproductive outcomes, with significant implications for improving fertility management in commercial goat farming. Although no significant differences were observed in progesterone levels, the administration of GnRH analogue reduced early embryonic mortality and improved reproductive outcomes, demonstrating its potential to enhance embryo survival and reproductive performance in goats.

Indexed as

Embryo TransferFertilityGoatHormonal TreatmentsProgesteroneReproductive Outcomes

Identifiers

PMID39543997
PMCPMC12061578

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.