ArticleCancer control : journal of the Moffitt Cancer Center
Racial and Ethnic Disparities in Colorectal Cancer Incidence Trends Across Regions of the United States From 2001 to 2020 - A United States Cancer Statistics Analysis.
Article in Cancer control : journal of the Moffitt Cancer Center. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Factors Associated with Ever Undergoing Colorectal Cancer Testing Among Adults in the United States.Diseases (Basel, Switzerland) · 2026Article
- Temporal Trends in Colorectal Cancer Associated With Type 2 Diabetes Mellitus in U.S. Adults, 1999-2023: A CDC Wonder Database Analysis-A Population-Based Cross-Sectional Study.Health science reports · 2026Article
- Interrogating the Mechanistic Link between Neighborhood Deprivation and Colorectal Cancer Risk through Transcriptomic Analysis of Normal Colorectal Biopsies.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2026Article
- Potential Prognostic and Metastatic Implications of MACC1 and MMP8 in Colorectal Cancer.Current issues in molecular biology · 2026Article
- Letter to editor on "Clinicopathological characteristics and biomarker alterations in early-onset vs. late-onset colorectal cancer: a systematic review and meta-analysis".International journal of surgery (London, England) · 2026Article
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7 authors.
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Abstract
backgroundColorectal cancer (CRC) incidence rates have been decreasing in the United States (US), but there is limited information about differences in these improvements among individuals from different racial and ethnic subgroups across different regions of the US.
methodsData from the National Program of Cancer Registries (NPCR) and the Surveillance, Epidemiology, and End Results (SEER) databases were used to examine trends in CRC incidence from 2001 to 2020 using a population-based retrospective cohort study. We obtained annual estimates of CRC incidence and used meta-regression analyses via weighted linear models to identify main effects and interactions that explained differences in CRC incidence trends among groups defined by race/ethnicity and US region while also considering CRC stage and sex. To summarize overall trends over time in incidence rates for specific racial and ethnic groups within and across US regions, we obtained average annual percentage change (AAPC) estimates.
resultsThe greatest differences in CRC incidence trends were among groups defined by race/ethnicity and US region. Non-Hispanic Black (NHB) persons had the largest declines in CRC incidence, with AAPC estimates ranging from -2.27 (95% CI: -2.49 to -2.06) in the South to -3.03 (95% CI: -3.59 to -2.47) in the West, but had higher-than-average incidence rates at study end. The AAPC estimate for American Indian/Alaska Native (AIAN) persons suggested no significant change over time (AAPC: -0.41, 95% CI: -2.51 to 1.73).
conclusionCRC incidence trends differ among racial/ethnic groups residing in different US regions. Notably, CRC incidence rates have not changed noticeably for AIAN persons from 2001-2020. These findings highlight the importance of reinvigorating collaborative efforts to develop geographic and population-specific screening and preventative approaches to reduce the CRC burden experienced by Native American communities and members of other minoritized groups.
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