Evidence map›Paper›PMID 39543863›Full record

ArticleKorean journal of radiology2024

Determining Disease Activity and Glucocorticoid Response in Thyroid-Associated Ophthalmopathy: Preliminary Study Using Dynamic Contrast-Enhanced MRI.

Hao Hu, Xiong-Ying Pu, Jiang Zhou, Wen-Hao Jiang, Qian Wu, Jin-Ling Lu, Fei-Yun Wu, Huan-Huan Chen, Xiao-Quan Xu

Abstract read
In one paragraph

Article in Korean journal of radiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
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  4. Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hao Hu *Department of Radiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.ORCID 0000-0002-7983-7377
Xiong-Ying Pu *Department of Radiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.ORCID 0009-0007-7166-4030
Jiang ZhouDepartment of Radiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.ORCID 0000-0003-1038-387X
Wen-Hao JiangDepartment of Radiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.ORCID 0000-0002-2390-6927
Qian WuDepartment of Radiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.ORCID 0000-0002-8638-3107
Jin-Ling LuDepartment of Radiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.ORCID 0009-0000-1037-1807
Fei-Yun WuDepartment of Radiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.ORCID 0000-0002-0343-0458
Huan-Huan ChenDepartment of Endocrinology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China. drchenhuanhuan@njmu.edu.cn.ORCID 0000-0003-0201-2059
Xiao-Quan XuDepartment of Radiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China. xiaoquanxu_1987@163.com.ORCID 0000-0001-5493-5256

Funding

Jiangsu Province Capability Improvement Project JSDW202243Jiangsu Province Hospital Clinical Capacity Enhancement Project JSPH-MC-2021-8NNSFC 81801659
6 · The paper itself

Abstract

objectiveTo assess the role of dynamic contrast-enhanced (DCE)-MRI of the extraocular muscles (EOMs) for determining the activity of thyroid-associated ophthalmopathy (TAO) and treatment response to glucocorticoids (GCs). MATERIALS AND

methodsWe prospectively enrolled 65 patients with TAO (41 active, 82 eyes; 24 inactive, 48 eyes). Twenty-two active patients completed the GC treatment and follow-up assessment, including 15 patients (30 eyes) and 7 patients (14 eyes), defined as responsive and unresponsive, respectively. Model-free (time to peak [TTP], area under the curve [AUC], and Slope

resultsActive patients exhibited significantly higher TTP at the 10th percentile (-10th), TTP-mean, and TTP at the 90th percentile (-90th); AUC-10th, AUC-mean, AUC-90th, and AUC-max; K

conclusionDCE-MRI-derived model-free and model-based parameters of EOMs can assist in the evaluation of TAO. In particular, TTP-mean and V

Indexed as

Contrast MediaGlucocorticoidsGraves OphthalmopathyMagnetic Resonance ImagingAdultAgedFemaleHumansMaleMiddle AgedOculomotor MusclesProspective StudiesTreatment OutcomeContrast MediaGlucocorticoidsDisease activityDynamic contrast-enhancedMagnetic resonance imagingThyroid-associated ophthalmopathyTreatment response

Identifiers

PMID39543863
PMCPMC11604342

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.