Evidence map›Paper›PMID 39543253›Full record

ArticleEye (London, England)2025

Associations of incident myopia and its development with related factors among school-aged children across different grades: a four-year longitudinal study.

Lan Guo, Jiayu Zhang, Yangfeng Guo, Yin Hu, Lili Wang, Xiao Yang, Ciyong Lu

Abstract readMulticenter Study
In one paragraph

Article in Eye (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Observational
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lan Guo *Department of Medical Statistics and Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou, 510080, China.
Jiayu Zhang *Department of Medical Statistics and Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou, 510080, China.
Yangfeng GuoHealth Promotion Center for Primary and Secondary Schools of Guangzhou Municipality, Guangzhou, China.
Yin HuState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China.
Lili WangState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China.
Xiao YangState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China. Yangx_zoc@163.com.ORCID http://orcid.org/0000-0001-5649-7763
Ciyong LuDepartment of Medical Statistics and Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou, 510080, China. luciyong@mail.sysu.edu.cn.ORCID http://orcid.org/0000-0003-4266-4967

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess the progression of myopia across different academic grades and investigate the associations between potential myopia-related factors and the incidence of myopia at various grade levels.

methodsWe utilized data from an ongoing longitudinal study that began with grade 1 students across 12 schools. Four waves of annual eye examinations and questionnaire surveys were conducted. Longitudinal analyses were performed on three groups: Group 1 (n = 1223, non-myopic in grade 1) examined factors in grade 1 associated with incident myopia in grade 2; Group 2 (n = 653, non-myopic in grade 2) investigated factors in grade 2 related to incident myopia in grade 3; and Group 3 (n = 746, non-myopic in grade 3) evaluated factors in grade 3 associated with incident myopia in grade 4.

resultsThe incidence of myopia increased from 4.3% in grade 2 to 21.6% in grade 4. Our findings revealed a consistent positive association between the number of myopic parents and incident myopia in grades 2, 3, and 4, respectively. Outdoor activity in earlier grades showed significant protective effects, reducing the risk of incident myopia in the subsequent grades 2 and 3 (e.g., in Group 1, adjusted HR 0.46 [95% CI 0.24 ~ 0.86]). However, no significant association was observed between outdoor activity in grade 3 and incident myopia in grade 4.

conclusionsIt is important to consider the grade level of schoolchildren when addressing myopia control. Implementing early-phase interventions, particularly those emphasizing outdoor activities, may help mitigate the onset and progression of myopia during the earlier school years.

Indexed as

MyopiaStudentsAdolescentChildDisease ProgressionFemaleHumansIncidenceLongitudinal StudiesMaleRefraction, OcularRisk FactorsSchoolsSurveys and Questionnaires

Identifiers

PMID39543253
PMCPMC11885601

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.