Evidence map›Paper›PMID 39543243›Full record

ArticleScientific reports2024

Synthesis and evaluation of vanillin Schiff bases as potential antimicrobial agents against ESBL-producing bacteria: towards novel interventions in antimicrobial stewardship.

Ruby Khan, Salma Rashid, Sumbal Khan, Yahya A Almutawif, Bakht Pari

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
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  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ruby KhanDepartment of System Biology and Engineering, Silesian University of Technology, Gliwice, Poland. ruby.khan@polsl.pl.ORCID 0000-0002-5419-1944
Salma RashidKhyber Medical University, Peshawar, Pakistan.
Sumbal KhanKhyber Girls Medical College, Hayatabad, Peshawar, Pakistan.ORCID 0009-0006-8703-7907
Yahya A AlmutawifDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, Taibah University, Madinah, Saudi Arabia.ORCID 0000-0002-5654-6139
Bakht PariPrincipal, Govt Nursing College, Lady Reading Hospital, Peshawar, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The escalating challenge of antimicrobial resistance necessitates the development of novel antibacterial agents. In this study, a series of five vanillin Schiff bases (SB-1 to SB-5) were synthesized from vanillin and various aromatic amines. The chemical structures of these compounds were characterized using Thin Layer Chromatography (TLC), Fourier Transform Infrared Spectroscopy (FT-IR), proton nuclear magnetic resonance (

Indexed as

Anti-Bacterial AgentsArtemiaBenzaldehydesbeta-LactamasesEscherichia coliMicrobial Sensitivity TestsPseudomonas aeruginosaSchiff BasesAnimalsHumansKlebsiella pneumoniaeAnti-Bacterial AgentsBenzaldehydesbeta-LactamasesSchiff BasesvanillinAntibacterial activityCytotoxicityDrug resistanceESBL-producing bacteriaVanillin Schiff bases

Identifiers

PMID39543243
PMCPMC11564564

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.