Evidence map›Paper›PMID 39543068›Full record

ReviewCell biochemistry and biophysics2025

Exploring the Updated Roles of Ferroptosis in Liver Diseases: Mechanisms, Regulators, and Therapeutic Implications.

Ting Ge, Yang Wang, Yiwen Han, Xiaofeng Bao, Chunfeng Lu

Abstract readReview
PubMed Publisher
In one paragraph

Review in Cell biochemistry and biophysics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ting GeSchool of Pharmacy, Nantong University, Nantong, Jiangsu, China.
Yang WangSchool of Pharmacy, Nantong University, Nantong, Jiangsu, China.
Yiwen HanSchool of Pharmacy, Nantong University, Nantong, Jiangsu, China.
Xiaofeng BaoSchool of Pharmacy, Nantong University, Nantong, Jiangsu, China.
Chunfeng LuSchool of Pharmacy, Nantong University, Nantong, Jiangsu, China. ntdxlcf@ntu.edu.cn.

Funding

Large Instruments Open Foundation of Nantong University KFJN2447Natural Science Research Project of Jiangsu Higher Education Institutions 22KJB360015Postgraduate Research & Practice Innovation Program of Jiangsu Province KYCX23_3439
6 · The paper itself

Abstract

Ferroptosis, a newly discovered mode of cell death, is a type of iron-dependent regulated cell death characterized by intracellular excessive lipid peroxidation and imbalanced redox. As the liver is susceptible to oxidative damage and the abnormal iron accumulation is a major feature of most liver diseases, studies on ferroptosis in the field of liver diseases are of great interest. Studies show that targeting the key regulators of ferroptosis can effectively alleviate or even reverse the deterioration process of liver diseases. System Xc

Indexed as

FerroptosisLiver DiseasesAnimalsHumansIronLipid PeroxidationIronCell deathFerroptosisFerroptosis modulatorsFerroptosis targetsLiver diseases

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.