Evidence map›Paper›PMID 39543023›Full record

ArticleDigestive diseases and sciences2024

Comparing Environmental Risk Factors at Diagnosis in Faroese and Danish Patients with Inflammatory Bowel Disease.

Kári Rubek Nielsen, Frederikke Agerbo Modin, Jóngerð Midjord, Amanda Vang, Marjun Á Fríðriksmørk Berbisá, Herborg Líggjasardóttir Johannesen, Jens Frederik Dahlerup, Vibeke Andersen, Anders Neumann, Jens Kjeldsen and 5 more

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Digestive diseases and sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

15 authors.

Kári Rubek NielsenMedical Centre, National Hospital of the Faroe Islands, Tórshavn, Faroe Islands.
Frederikke Agerbo ModinOmicron ApS, Søborg, Denmark.
Jóngerð MidjordMedical Centre, National Hospital of the Faroe Islands, Tórshavn, Faroe Islands.
Amanda VangFirum, Department of Biotechnology, Tórshavn, Faroe Islands.
Marjun Á Fríðriksmørk BerbisáVarðin Pelagic, Department of Development, Tvøoyri, Faroe Islands.
Herborg Líggjasardóttir JohannesenMedical Centre, National Hospital of the Faroe Islands, Tórshavn, Faroe Islands.
Jens Frederik DahlerupDepartment of Clinical Medicine, Faculty of Health, Aarhus University, Aarhus, Denmark.
Vibeke AndersenDepartment of Internal Medicine, Molecular Diagnostics and Clinical Research Unit, University Hospital of Southern Denmark, Aabenraa, Denmark.
Anders NeumannDepartment of Internal Medicine, Regional Hospital Viborg, Viborg, Denmark.
Jens KjeldsenDepartment of Medical Gastroenterology, Odense University Hospital, Odense, Denmark.
Natalia PedersenDepartment of Gastroenterology, Slagelse Hospital, Slagelse, Denmark.
Ebbe LangholzGastrounit D, Medical Section, Herlev and Gentofte University Hospital, Herlev, Denmark.
Pia MunkholmDepartment of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Turid Hammer *Department of Research, The National Hospital of the Faroe Islands, Tórshavn, Faroe Islands.
Johan Burisch *Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. johan.burisch@regionh.dk.

Funding

EU Horizon Europe program grant miGut-Health: personalised blueprint of intestinal health 101095470
6 · The paper itself

Abstract

backgroundThe incidence and prevalence of inflammatory bowel disease (IBD) in the Faroe Islands have increased drastically during the past 60 years, presumably due to changing environmental risk factors in a genetically susceptible population.

aimThis study investigated differing environmental factors present in Faroese and Danish patients.

methodsFrom 2010 to 2022, all incident Faroese patients with IBD were invited to complete the International Organization of IBD (IOIBD) questionnaire about environmental factors at the time of their diagnosis. The findings were compared to a cohort of incident Danish patients diagnosed between 2010 and 2011.

resultsQuestionnaires were completed by 293 of 388 Faroese patients (75%), of whom 15% (n = 45) had Crohn's disease (CD), 63% (n = 185) had ulcerative colitis (UC), and 22% (n = 63) had IBD unclassified (IBDU). Faroese patients with IBD and UC were found to have higher pertussis vaccination coverage (p < 0.05), and more childhood infections of measles and pertussis (p < 0.05). Faroese patients with IBD consumed more fast food and less fiber but consumed less sugar (p < 0.001) and more caffeine (p < 0.001). No differences were found regarding gender, having been breastfed, use of oral contraceptives, or the number of first-degree relatives with IBD; however, differences in smoking at diagnosis were found in a subset analysis of Faroese patients diagnosed in 2010-11 compared with Danish patients.

conclusionsFaroese patients with IBD were more exposed to some environmental risk factors prior to diagnosis than Danish patients. However, certain beneficial dietary habits were more common in Faroese patients than in Danish patients.

Indexed as

Crohn DiseaseAdultAgedColitis, UlcerativeDenmarkFemaleHumansIncidenceInflammatory Bowel DiseasesMaleMiddle AgedPrevalenceRisk FactorsSurveys and QuestionnairesYoung AdultCrohn’s diseaseEnvironmental factorsFaroe IslandsInflammatory bowel diseaseUlcerative colitis

Identifiers

PMID39543023
PMCPMC11602799

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